Effect of Curd Cheese on Metabolic Health in Adults

NCT07676838 | Completed

• 1 other identifier: OkanU-KO-3
• Study Type: interventional
• Target: 44
• Locations: 1 country
• Sites: 1

Brief Summary

This randomized controlled trial aims to evaluate the effects of a diet supplemented with curd cheese on anthropometric measurements, glycemia, and lipid profile in overweight adults. Participants aged 40-64 years with a BMI above 25 will be randomly assigned to an intervention group receiving 100 g of curd cheese at breakfast for 8 weeks or to a control group receiving a standard healthy diet without curd cheese. Primary outcomes include changes in fasting blood glucose and HbA1c, while secondary outcomes are changes in body composition, waist circumference, and lipid profile (HDL, LDL, triglycerides, total cholesterol).

Conditions

Cholesterol; Lipid Profile; Diabete Mellitus

Keywords

Lipid Profile; Glucose; Curd Cheese

Outcome Measures

Primary Outcomes (1)

• Change in HbA1c Levels

  To evaluate the effect of a curd cheese-supplemented diet on glycemic control by assessing changes in HbA1c levels from baseline to the end of the 8-week intervention.

  Baseline and after 8 weeks of intervention

Secondary Outcomes (6)

• Change in Fasting Glucose

  Baseline and after 8 weeks

• Change in Lipid Profile

  Baseline and after 8 weeks

• Change in Anthropometric Measures

  Baseline and after 8 weeks

• Change in Anthropometric Measures

  Baseline and after 8 weeks

• Change in Anthropometric Measures

  Baseline and after 8 weeks

Study Arms (2)

Curd Cheese Supplemented Diet Group

EXPERIMENTAL

Intervention Group - Arm Description: Participants in this arm follow a customized dietary plan for 8 weeks that includes daily servings of curd cheese. The diet is balanced for energy and macronutrient distribution according to individual needs. Curd cheese, as a high-quality protein and calcium source, is included to assess its specific effects on glucose and lipid parameters. This arm is designed to evaluate the unique metabolic effects of curd cheese supplementation compared to the control group.

Dietary Supplement: Curd Cheese Supplemented Diet

Standard Diet Group

NO INTERVENTION

Participants in this arm follow a standard dietary plan for 8 weeks without curd cheese. The diet is balanced according to individual energy and macronutrient needs. This arm serves as a comparison group to determine the specific effects of curd cheese supplementation observed in the intervention group.

Interventions

Curd Cheese Supplemented Diet DIETARY_SUPPLEMENT

This intervention consists of daily consumption of 100 grams of curd cheese as part of a personalized dietary plan for 8 weeks. Curd cheese is consumed at breakfast and integrated into the participants' regular meal plans. The diet is balanced for total energy and macronutrient distribution according to individual nutritional needs. All participants in this arm receive the same type and brand of curd cheese throughout the intervention period.

Curd Cheese Supplemented Diet Group

Eligibility Criteria

• Age: 40 Years - 64 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Individuals aged 40-64 years.
• Body Mass Index (BMI) greater than 25 kg/m².
• Individuals who voluntarily applied to the Darıca Healthy Life Center and agreed to participate in the study.
• Individuals who have had HbA1c, glucose, and lipid profile measurements within the past month, or will have these measurements taken as part of this study.
• Individuals who are able to comply with the curd cheese-supplemented dietary intervention for at least 8 weeks.
• Individuals who have signed the written informed consent form.

You may not qualify if:

• Individuals diagnosed with diabetes mellitus.
• Individuals with chronic diseases such as renal, hepatic, or cardiac failure.
• Individuals with lactose intolerance or allergy to milk and dairy products.
• Pregnant or lactating women.
• Individuals with restricted protein intake for any medical reason.
• Individuals who have participated in another dietary intervention program within the last 3 months.
• Individuals diagnosed with psychiatric disorders requiring regular treatment.
• Individuals with irregular lifestyles or communication difficulties that may prevent adherence to the dietary intervention.

Sponsors & Collaborators

• Süleyman Kılıç: lead
• Halic University: collaborator

Study Sites (1)

Darıca Healthy Life Center

Kocaeli, DARICA, 41700, Turkey (Türkiye)

Location

Related Publications (4)

• Kataoka Y, Kamijo YI, Ogawa Y, Sumiyoshi E, Nakae M, Ikegawa S, Manabe K, Morikawa M, Nagata M, Takasugi S, Masuki S, Nose H. Effects of hypervolemia by protein and glucose supplementation during aerobic training on thermal and arterial pressure regulations in hypertensive older men. J Appl Physiol (1985). 2016 Oct 1;121(4):1021-1031. doi: 10.1152/japplphysiol.00033.2016. Epub 2016 May 19.

  PMID: 27197855 BACKGROUND

• Vogtschmidt YD, Raben A, Faber I, de Wilde C, Lovegrove JA, Givens DI, Pfeiffer AFH, Soedamah-Muthu SS. Is protein the forgotten ingredient: Effects of higher compared to lower protein diets on cardiometabolic risk factors. A systematic review and meta-analysis of randomised controlled trials. Atherosclerosis. 2021 Jul;328:124-135. doi: 10.1016/j.atherosclerosis.2021.05.011. Epub 2021 May 26.

  PMID: 34120735 BACKGROUND

• Zhang M, Dong X, Huang Z, Li X, Zhao Y, Wang Y, Zhu H, Fang A, Giovannucci EL. Cheese consumption and multiple health outcomes: an umbrella review and updated meta-analysis of prospective studies. Adv Nutr. 2023 Sep;14(5):1170-1186. doi: 10.1016/j.advnut.2023.06.007. Epub 2023 Jun 15.

  PMID: 37328108 BACKGROUND

• Jakubowicz D, Froy O, Ahren B, Boaz M, Landau Z, Bar-Dayan Y, Ganz T, Barnea M, Wainstein J. Incretin, insulinotropic and glucose-lowering effects of whey protein pre-load in type 2 diabetes: a randomised clinical trial. Diabetologia. 2014 Sep;57(9):1807-11. doi: 10.1007/s00125-014-3305-x. Epub 2014 Jul 10.

  PMID: 25005331 BACKGROUND

MeSH Terms

Conditions

Diabetes Mellitus

Condition Hierarchy (Ancestors)

Glucose Metabolism Disorders; Metabolic Diseases; Nutritional and Metabolic Diseases; Endocrine System Diseases

Study Officials

• Ahmet M GÜNAL, PhD, RD

  Haliç University

  PRINCIPAL INVESTIGATOR

• Salim YILMAZ, PhD

  Acıbadem Mehmet Ali Aydınlar University

  STUDY DIRECTOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Masking Details: This study is open-label; there is no masking. Both participants and investigators are aware of group assignments.
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Clinical Dietician, MSc

Model Details: This is a parallel-group, randomized controlled trial. Participants are randomly assigned to either the intervention group, receiving a dietary plan supplemented with curd cheese, or the control group, receiving a standard dietary plan without curd cheese. Both groups are followed for 8 weeks to assess changes in glucose and lipid parameters. The study is open-label; participants and investigators are aware of group assignments.

Study Record Dates

• First Submitted: June 16, 2026
• First Posted: June 30, 2026
• Study Start: December 12, 2025
• Primary Completion: May 22, 2026
• Study Completion: June 16, 2026
• Last Updated: June 30, 2026

Record last verified: 2026-06

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)