NCT07675655

Brief Summary

To investigate the differences between adding Mulligan mobilization and PNF to the conventional physical therapy program on shoulder pain, function, shoulder muscles strength, glenohumeral flexion, abduction, external rotation, and internal rotation ROM, scapular symmetry, and pectoralis minor length in patients with SIS.

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
69

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Sep 2025

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 2, 2025

Completed
9 months until next milestone

First Submitted

Initial submission to the registry

June 9, 2026

Completed
21 days until next milestone

First Posted

Study publicly available on registry

June 30, 2026

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2026

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2026

Completed
Last Updated

June 30, 2026

Status Verified

May 1, 2026

Enrollment Period

11 months

First QC Date

June 9, 2026

Last Update Submit

June 27, 2026

Conditions

Subacromial Impingement Syndrome

Keywords

Rotator Cuff Impingement SyndromePROPRIOCEPTIVE NEUROMUSCLAR FACILITATION TECHNIQUEmulligan mobilization

Outcome Measures

Primary Outcomes (3)

  • The Shoulder Pain and Disability Index (SPADI)

    assesses pain and disability in shoulder pathology. Patients answer five questions related to pain and eight questions related to function

    at baseline and after 6 weeks post intervention

  • Shoulder ROM

    the smartphone inclinometer will be used to perform clinical measurements of shoulder motion (Flexion, Abduction, External Rotation in 90- of Abduction, Internal Rotation in 90- of Abduction)

    at baseline and after 6 weeks post intervention

  • The Timed Functional Arm and Shoulder Test (TFAST)

    Task 1: Hand to Head and Back (HHB) 30s Movement: Move arm from the side to touch the back of the head (palm preferred), then move down to touch the small of the back with the back of the hand. Scoring: 1 rep per head touch. Task 2: Wall Wash (Inward/Outward) 60s per direction Movement: Move a towel in a 12-inch diameter circle at shoulder height, touching 4 drawn marks. Start at the top mark. Scoring: 1 rep each time the hand passes the top mark. Done clockwise and counter-clockwise. Task 3: Gallon-Jug Lift - 30s Movement: Lift a 3.78 kg jug from a 36-inch high counter to lightly tap a shelf 20 inches above it, then lower it without resting. Scoring: 1 rep per shelf tap. Total TFAST Score Calculation To equalize all tasks for a 30-second timeframe, the final score is calculated using this formula: \[HHB + (wall wash inward and outward/4) + gallon-jug lift\]

    at baseline and after 6 weeks post-intervention

Secondary Outcomes (3)

  • Measuring isometric strength with Hand-held sphygmomanometer

    at baseline and after 6 weeks post-intervention

  • The Modified Lateral Scapular Slide test

    at baseline and after 6 weeks post-intervention

  • Pectoralis minor length test

    at baseline and after 6 weeks post-intervention

Study Arms (3)

standard conventional Program

ACTIVE COMPARATOR

patients receive conventional program alone, include strengthening for scapular stabilizers, Posterior shoulder stretching exercises (PSSEs) (modified cross-body stretch and modified sleeper stretch), stretching for pectoralis minor and transcutaneous electrical nerve stimulation (TENS).

Other: Standard conventional program

PNF technique + same standard conventional program

EXPERIMENTAL

patients receive PNF diagonal pattern exercise program in addition to the same conventional program as in group A

Other: Proprioceptive neuromuscular facilitation (PNF) +Standard program

MWM+ same standard conventional program

EXPERIMENTAL

patients receive a posterolateral MWM in addition to conventional program as in group A.

Other: MWM +Standard program

Interventions

Standard conventional programOTHER

Patients receive standard conventional program inform of exercise and TENS

standard conventional Program
Proprioceptive neuromuscular facilitation (PNF) +Standard programOTHER

patients receive Proprioceptive neuromuscular facilitation (PNF) +Standard conventionalprogram

PNF technique + same standard conventional program
MWM +Standard programOTHER

patients receive MWM +Standard program

MWM+ same standard conventional program

Eligibility Criteria

Age20 Years - 40 Years
Sexall(Gender-based eligibility)
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Sixty nine Males and females subjects with SIS, age between 20-40 years old and body mass index (BMI) 18-27.9 kg/m2
  • The SIS group will be limited to patients who had history of shoulder pain of \>1-week duration.
  • Pain localized at the proximal anterolateral shoulder region.
  • Patients with subacromial pain syndrome with positive results of 3 of 5 tests: painful arc, pain or weakness with resisted external rotation, Neer test, Hawkins Kennedy test, and Jobe/empty can test.

You may not qualify if:

  • Patients will be excluded if they had any of the following conditions:
  • Open wounds, infection, acute injuries, swelling, rheumatoid arthritis, reflex sympathetic syndrome, or adhesive capsulitis.
  • BMI greater than 28 kg/m².
  • History of shoulder girdle fractures and dislocation, shoulder surgery in the last 12 months or full thickness rotator cuff tear.
  • History of systemic or neurological disorder, cervical radiculopathy and subjects who had received physical therapy treatment for their shoulder within the past three months.
  • History of corticosteroid injection in the shoulder region less than 12 weeks previously.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Magdy Eshak

Sohag, Tahta, Egypt

RECRUITING

Related Links

MeSH Terms

Conditions

Shoulder Impingement Syndrome

Interventions

Muscle Stretching Exercises

Condition Hierarchy (Ancestors)

Joint DiseasesMusculoskeletal DiseasesShoulder InjuriesWounds and Injuries

Intervention Hierarchy (Ancestors)

Exercise TherapyRehabilitationAftercareContinuity of Patient CarePatient CareTherapeuticsPhysical Therapy ModalitiesExerciseMotor ActivityMovementMusculoskeletal Physiological PhenomenaMusculoskeletal and Neural Physiological Phenomena

Central Study Contacts

Mina Magdy, Master

CONTACT

01277660470mina.magdy.9595@gmail.com

Marihan zakaria, Lecturer

CONTACT

01201227971marihan_aziz@cu.edu.eg

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Model Details: Group A: will receive a program of conventional exercise include strengthening for scapular stabilizers, Posterior shoulder stretching exercises (PSSEs) (modified cross-body stretch and modified sleeper stretch), stretching for pectoralis minor and transcutaneous electrical nerve stimulation (TENS). Group B : will receive PNF diagonal pattern exercise program in addition to conventional Exercise as in group A. Group C : will receive a posterolateral MWM in addition to conventional Exercise as in group A.
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Lecturer at the Faculty of Physical Therapy

Study Record Dates

First Submitted

June 9, 2026

First Posted

June 30, 2026

Study Start

September 2, 2025

Primary Completion

August 1, 2026

Study Completion

August 1, 2026

Last Updated

June 30, 2026

Record last verified: 2026-05

Locations

EG(1)