Cognitive Reserve and Post-Fatigue Recovery in Older Adults

NCT07667985 | Recruiting

• 1 other identifier: 1280-1280-11
• Study Type: observational
• Target: 400
• Locations: 1 country
• Sites: 1

Brief Summary

As people grow older, it is common to experience a drop in physical stamina and memory functions. This can make recovering from daily physical and mental fatigue more difficult, which directly impacts an individual's independent daily life and overall quality of life. "Cognitive reserve" is a term that describes the brain's built-in resilience. Built over a lifetime through education, work, and social activities, a higher cognitive reserve acts like a buffer, helping the brain adapt to stress and aging. While research shows that a high cognitive reserve protects against conditions like dementia, we still do not fully understand how it helps older adults bounce back from normal, everyday physical and mental exhaustion. The goal of this study is to investigate how cognitive reserve levels influence how individuals aged 65 and older perceive their recovery after experiencing physical and mental fatigue. What the Study Involves The researchers will evaluate participants aged 65 and older to measure their baseline cognitive reserve levels. The study will look closely at how these levels affect the participants': Ability to cope with daily physical and mental fatigue. Need for rest and rest patterns. Time and ability to return to normal daily activities. Overall perception of their mental and physical recovery. Expected Outcome By understanding this relationship, the study aims to fill a gap in medical literature and help healthcare providers design better, more personalized rehabilitation and lifestyle support programs to improve the quality of life for older adults.

Conditions

Cognitive Reserve; Aging; Mental Fatigue; Fatigue; Recovery of Function

Keywords

aging; cognitive reserve; fatigue; Post-Fatigue Recovery

Outcome Measures

Primary Outcomes (1)

• Cognitive Reserve Level

  Cognitive Reserve Index questionnaire (CRIq):It assesses an individual's cognitive reserve by compiling information about that individual's entire adult life. The assessment will be conducted with the aid of a guide containing guidelines.

  Baseline

Secondary Outcomes (1)

• Perception of Coping and Recovery After Mental and Physical Fatigue

  Baseline

Eligibility Criteria

• Age: 65 Years - 90 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The study population consists of community-dwelling older adults aged 65 and over.The sample will include individuals who are independently mobile, able to perform activities of daily living, and free of severe cognitive impairments or acute medical conditions that would prevent them from understanding the research protocol or reporting their perception of fatigue and recovery.

You may qualify if:

• being 65 years of age or older,
• not having any neurological, psychiatric, or systemic disease that would affect one's mental state, and not using any medication for these conditions.

You may not qualify if:

• Being younger than 65 years old,
• having an illness or taking medication that affects mental health, or being
• unable to complete the questionnaires.

Sponsors & Collaborators

• Uşak University: lead

Study Sites (1)

Uşak University

Uşak, Uşak, 64000, Turkey (Türkiye)

RECRUITING

MeSH Terms

Conditions

Mental Fatigue; Fatigue

Condition Hierarchy (Ancestors)

Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Behavioral Symptoms; Behavior

Study Officials

• Elif Tuncay, PhD

  Uşak University

  PRINCIPAL INVESTIGATOR

• Kevser GÜRSAN, PhD

  Uşak University

  STUDY DIRECTOR

• Emre Cengiz, PhD

  Uşak University

  STUDY CHAIR

• Elif Gür Kabul, PhD

  Uşak University

  STUDY CHAIR

Central Study Contacts

Elif Tuncay, PhD

CONTACT

+90 276 221 2121 Extension: 30; elif.tuncay@usak.edu.tr

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor

Study Record Dates

• First Submitted: June 19, 2026
• First Posted: June 25, 2026
• Study Start: June 20, 2026
• Primary Completion (Estimated): September 21, 2026
• Study Completion (Estimated): September 22, 2026
• Last Updated: June 25, 2026

Record last verified: 2026-06

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)