NCT07665385

Brief Summary

clinical trial: The main aim of this study is to compare the effectiveness of Cognitive Behavioral Therapy (CBT) and Sound Therapy, both individually and in combination, in the management of patients with chronic subjective tinnitus and to evaluate their impact on decreasing tinnitus severity, psychological wellbeing and quality of life. Patients will be randomly divided into three groups:

  • Group A: patients will receive Sound Therapy.
  • Group B: patients will receive Cognitive Behavioral Therapy (CBT).
  • Group C: patients will receive Combined CBT + Sound Therapy.

Trial Health

63
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Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
60

participants targeted

Target at P25-P50 for not_applicable

Timeline
4mo left

Started Jun 2026

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress36%
Jun 2026Dec 2026

Study Start

First participant enrolled

June 10, 2026

Completed
1 day until next milestone

First Submitted

Initial submission to the registry

June 11, 2026

Completed
13 days until next milestone

First Posted

Study publicly available on registry

June 24, 2026

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 10, 2026

Expected
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 10, 2026

Last Updated

June 30, 2026

Status Verified

June 1, 2026

Enrollment Period

3 months

First QC Date

June 11, 2026

Last Update Submit

June 26, 2026

Conditions

Keywords

Sound TherapyCognitive Behavioral TherapyChronic TinnitusSubjective TinnitusTinnitus

Outcome Measures

Primary Outcomes (1)

  • Primary outcome: Changes in tinnitus severity

    Assessment of tinnitus severity using the Tinnitus Functional Index (TFI) . Higher scores indicate greater tinnitus severity. the TFI total score ranges from 0 to 100, with higher score s indicating greater tinnitus severity and functional impact

    Baseline, immediately after completion of treatment , and 3 months after completion of treatment

Secondary Outcomes (2)

  • chang in Visual Analog Scale (VAS) score

    Baseline, immediately after completion of treatment , and 3 months after completion of treatment

  • change in Tinnitus Handicap Inventory (THI) score

    Baseline, immediately after completion of treatment , and 3 months after completion of treatment

Study Arms (3)

Group A: patients will receive Sound Therapy

ACTIVE COMPARATOR
Behavioral: Group A: sound therapy

Group B: patients will receive Cognitive Behavioral Therapy (CBT).

ACTIVE COMPARATOR
Behavioral: Group B: Cognitive Behavioral Therapy

Group C: patients will receive Combined CBT + Sound Therapy.

ACTIVE COMPARATOR
Behavioral: Group A: sound therapyBehavioral: Group B: Cognitive Behavioral TherapyBehavioral: Group C: Combined CBT + Sound Therapy

Interventions

Group C: Combined Therapy • Patients will receive both sound therapy and CBT simultaneously following the same protocol as above.

Group C: patients will receive Combined CBT + Sound Therapy.

Group A: Sound Therapy * Patients will receive individualized sound therapy using broadband noise or tinnitus maskers. * Daily use recommended for 2-4 hours/day. * Duration: 6 weeks. * Patient will be instructed on habituation-based listening techniques

Group A: patients will receive Sound TherapyGroup C: patients will receive Combined CBT + Sound Therapy.

Group B: Cognitive Behavioral Therapy (CBT) • Structured CBT program consisting of 6 sessions over 6 weeks. Each session categorization: * Psychoeducation about tinnitus * Cognitive restructuring of negative thoughts * Relaxation techniques (breathing exercises, muscle relaxation) * Attention diversion strategies * Sleep hygiene education

Group B: patients will receive Cognitive Behavioral Therapy (CBT).Group C: patients will receive Combined CBT + Sound Therapy.

Eligibility Criteria

Age18 Months - 65 Months
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)

You may qualify if:

  • o Age: 18-65 years.
  • Hearing level: Patients with normal hearing or mild to moderate sensorineural hearing loss (to ensure homogeneity of the sample) (National Institute for Health and Care Excellence, 2020)
  • Complaint: patients with chronic subjective tinnitus (\> 3 months).
  • Psychological state: Patients with stable general and psychological condition.

You may not qualify if:

  • o Age: \<18, \>65 years
  • Hearing level: Patients with severe hearing loss not suitable for sound therapy
  • Complaint: Objective tinnitus (vascular or muscular origin)
  • Psychological state: Patients with active psychiatric disorders requiring immediate intervention.
  • Active middle or external ear disease

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Sohag faculty of medicine

Sohag, Egypt

Location

MeSH Terms

Conditions

Tinnitus

Condition Hierarchy (Ancestors)

Hearing DisordersEar DiseasesOtorhinolaryngologic DiseasesSensation DisordersNeurologic ManifestationsNervous System DiseasesSigns and SymptomsPathological Conditions, Signs and Symptoms

Central Study Contacts

Aya Ahmed Elsayed Abdelaal, Resident doctor

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Masking Details
Masking Description
Purpose
TREATMENT
Intervention Model
PARALLEL
Model Details: Model Description
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Resident at Audio-Vestibular unit ENT department at Sohag university hospital

Study Record Dates

First Submitted

June 11, 2026

First Posted

June 24, 2026

Study Start

June 10, 2026

Primary Completion (Estimated)

September 10, 2026

Study Completion (Estimated)

December 10, 2026

Last Updated

June 30, 2026

Record last verified: 2026-06

Locations