Nasal Packing After Turbinoplasty

NCT07663929 | Completed

• 1 other identifier: KFSIRB200-1082
• Study Type: interventional
• Target: 135
• Locations: 1 country
• Sites: 1

Brief Summary

This study aims to to compare postoperative pain, patient comfort, and hemostatic safety among four non-absorbable nasal packing techniques following microdebrider-assisted inferior turbinoplasty (MAIT) and to identify the most effective low-cost packing option.

Conditions

Nasal Packing

Outcome Measures

Primary Outcomes (2)

• Pain intensity

  1.Pain intensity Assessed using the Visual Analogue Scale (VAS) (0 = no pain, 10 = worst imaginable pain)

  We assesed pain during first 48 hours postoperative.

• Bleeding after packing removal Assessed using a 4-point grading scale

  Grade 0 = no bleeding Grade 1 = oozing Grade 2 = continuous bleeding Grade 3 = bleeding requiring intervention or control in the operating room

  We assesed bleeding immediately after nasal packing removal

Secondary Outcomes (1)

• Nasal fullness/pressure sensation

  We assesed it during first 48 hours postoperative.

Study Arms (4)

Standard bilateral Merocel® nasal tampons

ACTIVE COMPARATOR

Procedure: Standard bilateral Merocel® nasal tampons packing after Microdebrider-assisted inferior turbinoplasty

A Merocel® tampon enclosed within the finger portion of a sterile powder-free latex surgical glove

ACTIVE COMPARATOR

Procedure: A Merocel® tampon was enclosed within the finger portion of a sterile powder-free latex surgical glove after Microdebrider-assisted inferior turbinoplasty

Merocel® tampons were coated with a thin uniform layer of topical broad-spectrum antibiotic ointment

ACTIVE COMPARATOR

Procedure: Merocel® tampons were coated with a thin uniform layer of topical broad-spectrum antibiotic ointment after microdebrider-assisted inferior turbinoplasty

sterile ribbon gauze impregnated with white petroleum jelly (paraffin)

ACTIVE COMPARATOR

Procedure: terile ribbon gauze impregnated with white petroleum jelly (paraffin) after microdebrider-assisted inferior turbinoplasty

Interventions

Standard bilateral Merocel® nasal tampons packing after Microdebrider-assisted inferior turbinoplasty PROCEDURE

Standard bilateral Merocel® nasal tampons (Medtronic, USA) were inserted in their dry compressed form. Prior to insertion, each tampon was trimmed according to the dimensions of the patient's nasal cavity. Following contact with nasal secretions, the Merocel expanded to provide gentle and uniform pressure over the operative site.

Standard bilateral Merocel® nasal tampons

Merocel® tampons were coated with a thin uniform layer of topical broad-spectrum antibiotic ointment after microdebrider-assisted inferior turbinoplasty PROCEDURE

Merocel® tampons were coated with a thin uniform layer of topical broad-spectrum antibiotic ointment, such as fusidic acid 2% plus corticosteroids, prior to bilateral insertion. This modification was intended to provide localized antimicrobial coverage while preserving the hemostatic effect of the packing material.

Merocel® tampons were coated with a thin uniform layer of topical broad-spectrum antibiotic ointment

terile ribbon gauze impregnated with white petroleum jelly (paraffin) after microdebrider-assisted inferior turbinoplasty PROCEDURE

Sterile ribbon gauze impregnated with white petroleum jelly (paraffin) was loosely packed into each nasal cavity in a layered accordion-like fashion, beginning at the nasal floor and progressing posteriorly. Packing density was standardized to achieve adequate hemostasis while avoiding excessive pressure on the nasal mucosa.

sterile ribbon gauze impregnated with white petroleum jelly (paraffin)

A Merocel® tampon was enclosed within the finger portion of a sterile powder-free latex surgical glove after Microdebrider-assisted inferior turbinoplasty PROCEDURE

A Merocel® tampon was enclosed within the finger portion of a sterile powder-free latex surgical glove. The glove finger was then partially stripped to expose portions of the Merocel surface while retaining a thin latex interface, thereby preventing the glove from acting as a complete barrier and allowing contact between the Merocel and surrounding nasal secretions. This modification preserved the expansion and absorptive properties of the Merocel while creating a smoother, less adherent outer surface.

A Merocel® tampon enclosed within the finger portion of a sterile powder-free latex surgical glove

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Adults aged 18-65 years.
• Chronic bilateral nasal obstruction secondary to inferior turbinate hypertrophy.
• Failure of conservative medical management for at least 3 months, including intranasal corticosteroids and oral antihistamines.
• Positive decongestion test showing ≥30% improvement in anterior nasal cavity volume (V2-5 cm) on acoustic rhinometry after topical xylometazoline 0.5%, confirming predominantly mucosal rather than bony hypertrophy.
• Inferior turbinate hypertrophy grade 3 or 4 according to the Camacho classification system.

You may not qualify if:

• Significant nasal septal deviation affecting the nasal valve region.
• Internal or external nasal valve collapse or stenosis.
• Chronic rhinosinusitis with or without nasal polyposis.
• Previous nasal or paranasal sinus surgery.
• Coagulopathy or current anticoagulant therapy.
• Uncontrolled systemic disease.
• Pregnancy.
• Active smoking.
• Known allergic sensitization to any component of the nasal packing materials.

Sponsors & Collaborators

• Kafrelsheikh University: lead

Study Sites (1)

Kafrelsheikh University Hospitals

Kafrelsheikh, Egypt

Location

MeSH Terms

Interventions

Petrolatum; Paraffin

Intervention Hierarchy (Ancestors)

Hydrocarbons; Organic Chemicals

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: June 14, 2026
• First Posted: June 23, 2026
• Study Start: January 1, 2026
• Primary Completion: May 6, 2026
• Study Completion: June 3, 2026
• Last Updated: June 23, 2026

Record last verified: 2026-01

Locations

EG (1)