A Prospective , Split-mouth, Clinical Study of Orthodontic Titanium Miniscrews With Machined and Acid-etched Surfaces.

NCT07662434 | Completed

• 1 other identifier: FUCDCLINIC-2406
• Study Type: interventional
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

Primary goal of this study to check the stability of miniscrews used in orthodontic treatment in order to evaluate the success of the treatment.

Conditions

Malaligned Teeth; Crowding

Keywords

Miniscrews; Acid-etched Miniscrews

Outcome Measures

Primary Outcomes (1)

• Primary Stability of of machined and acid-etched miniscrews

  Absence of clinical stability of miniscrews (\>1mm)

  After one month of insertion

Study Arms (2)

experimental group: Acid etcehd miniscrews

EXPERIMENTAL

Placement of surface treated screws

Device: miniscrews placement

Control Group with conventional miniscrews

PLACEBO COMPARATOR

Non-surface treated miniscrews

Device: miniscrews placement

Interventions

miniscrews placement DEVICE

Placement of miniscrews under local anesthesia in both groups

Control Group with conventional miniscrews; experimental group: Acid etcehd miniscrews

Eligibility Criteria

• Age: 13 Years - 25 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64)

You may qualify if:

• Fixed appliance treatment with or without premolar extraction One or more miniscrews for same reason in each quadrant of maxilla or mandible Patient over 13 years Patient with permanent dentition\\ Treatment plan should include miniscrews

You may not qualify if:

• Severe craniofacial deformities such as cleft lip and palate History of bone disease Cases with high expectation of failure due to anatomical limitation such as sinus pneumatization Narrow interproximal alveolar bone Attached gingiva deficiency Mixed Dentition

Sponsors & Collaborators

• Foundation University Islamabad: lead

Study Sites (1)

Foundation University College of Dentistry and Hospital

Islamabad, Federal, 44000, Pakistan

Location

Related Publications (6)

• Yoo SH, Park YC, Hwang CJ, Kim JY, Choi EH, Cha JY. A comparison of tapered and cylindrical miniscrew stability. Eur J Orthod. 2014 Oct;36(5):557-62. doi: 10.1093/ejo/cjt092. Epub 2013 Dec 19.

  PMID: 24355870 RESULT

• Chen YJ, Chang HH, Huang CY, Hung HC, Lai EH, Yao CC. A retrospective analysis of the failure rate of three different orthodontic skeletal anchorage systems. Clin Oral Implants Res. 2007 Dec;18(6):768-75. doi: 10.1111/j.1600-0501.2007.01405.x. Epub 2007 Sep 14.

  PMID: 17868386 RESULT

• Chang C, Liu SS, Roberts WE. Primary failure rate for 1680 extra-alveolar mandibular buccal shelf mini-screws placed in movable mucosa or attached gingiva. Angle Orthod. 2015 Nov;85(6):905-10. doi: 10.2319/092714.695.1. Epub 2015 Jan 20.

  PMID: 25603272 RESULT

• Choi SH, Jang SH, Cha JY, Hwang CJ. Evaluation of the surface characteristics of anodic oxidized miniscrews and their impact on biomechanical stability: An experimental study in beagle dogs. Am J Orthod Dentofacial Orthop. 2016 Jan;149(1):31-8. doi: 10.1016/j.ajodo.2015.06.020.

  PMID: 26718375 RESULT

• Gansukh O, Jeong JW, Kim JW, Lee JH, Kim TW. Mechanical and Histological Effects of Resorbable Blasting Media Surface Treatment on the Initial Stability of Orthodontic Mini-Implants. Biomed Res Int. 2016;2016:7520959. doi: 10.1155/2016/7520959. Epub 2016 Jan 28.

  PMID: 26942200 RESULT

• Park HJ, Choi SH, Choi YJ, Park YB, Kim KM, Yu HS. A prospective, split-mouth, clinical study of orthodontic titanium miniscrews with machined and acid-etched surfaces. Angle Orthod. 2019 May;89(3):411-417. doi: 10.2319/031618-211.1. Epub 2018 Dec 5.

  PMID: 30516419 RESULT

MeSH Terms

Conditions

Crowding

Condition Hierarchy (Ancestors)

Spatial Behavior; Behavior

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor

Study Record Dates

• First Submitted: June 11, 2026
• First Posted: June 23, 2026
• Study Start: June 20, 2024
• Primary Completion: October 2, 2025
• Study Completion: December 2, 2025
• Last Updated: June 23, 2026

Record last verified: 2026-06

Data Sharing

• IPD Sharing: Will not share

Locations

PA (1)