NCT07655830

Brief Summary

This study aims to evaluate the changes between preoperative and postoperative serum chloride levels in patients undergoing HoLEP surgery and to investigate the metabolic and clinical effects of this change. The study is observational, and no additional interventions will be performed.

Trial Health

65
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Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
45

participants targeted

Target at P25-P50 for all trials

Timeline
2mo left

Started Jul 2026

Shorter than P25 for all trials

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress33%
Jul 2026Sep 2026

First Submitted

Initial submission to the registry

June 5, 2026

Completed
13 days until next milestone

First Posted

Study publicly available on registry

June 18, 2026

Completed
16 days until next milestone

Study Start

First participant enrolled

July 4, 2026

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 30, 2026

Expected
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

September 30, 2026

Last Updated

June 18, 2026

Status Verified

June 1, 2026

Enrollment Period

2 months

First QC Date

June 5, 2026

Last Update Submit

June 13, 2026

Conditions

HoLEP (Holmium Laser Enucleation of Prostate)HyperchloremiaPerioperative Management

Outcome Measures

Primary Outcomes (1)

  • Change in serum chloride level

    Perioperative

Secondary Outcomes (2)

  • irrigation volume

    Perioperative

  • Arter blood gas

    Perioperative

Study Arms (1)

Patients undergoing elective HoLEP surgery.

Procedure: HoLEP surgery

Interventions

HoLEP surgeryPROCEDURE

All parameters are part of routine clinical practice; no additional examinations are required

Patients undergoing elective HoLEP surgery.

Eligibility Criteria

Age18 Years+
Sexmale
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Patients scheduled for elective HoLEP surgery.

You may qualify if:

  • Patients scheduled for elective HoLEP surgery.
  • Patients providing written informed consent

You may not qualify if:

  • Preoperative metabolic acidosis.
  • Advanced renal failure.
  • Emergency surgery.
  • Missing data.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assos prof

Study Record Dates

First Submitted

June 5, 2026

First Posted

June 18, 2026

Study Start

July 4, 2026

Primary Completion (Estimated)

August 30, 2026

Study Completion (Estimated)

September 30, 2026

Last Updated

June 18, 2026

Record last verified: 2026-06