Intraoperative Analysis of Knee Kinematics During ACL Reconstruction - an Exploratory Study

NCT07655726 | Not Yet Recruiting

• 1 other identifier: 2026-A00868-43
• Study Type: interventional
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

Reconstruction of anterior cruciate ligament (ACL) is a common procedure in orthopaedic surgery, aimed at restoring stability to your knee. This procedure involves performing an anterior cruciate ligament (ACL) graft and an anterolateral ligament (ALL) graft. Despite technological advances and improvements in surgical techniques, failure rates remain high. In this context, a better understanding of knee movements (the position of the femur and tibia, as well as the ligaments) during flexion whilst reconstructing your ACL could improve the precision of reconstructions and reduce the long-term failure rate. Using a surgical navigation system, it is possible to record data on the positioning of the femur and tibia during flexion and extension. This type of morpho-functional analysis of knee kinematics during ACL reconstruction has never been carried out before.

Conditions

ACL - Anterior Cruciate Ligament Rupture

Keywords

ACL rupture; Knee cinematics

Outcome Measures

Primary Outcomes (1)

• Knee cinematics

  The kinematic changes in the knee resulting from ACL reconstruction in flexion (at 90° and 45°) and in extension will be assessed intraoperatively, based on the following distances measured before and after placement of the ACL graft: * Femoro-tibial distance for the insertion of the LLE * Femoro-tibial distance for the insertion of the LLI * Femoro-tibial distance for the insertion of the ACL (before graft placement) * Distance between the centres of the intra-articular openings of the femoral and tibial tunnels (after graft placement) * Femoro-tibial distance for the insertion of the PCL

  Day 0

Study Arms (1)

Knee cinematics

EXPERIMENTAL

Intraoperative morpho-functional analysis of the injured knee

Procedure: Knee Cinematics

Interventions

Knee Cinematics PROCEDURE

The pins used for ACL reconstruction will serve as a mount for the optical markers used to record the position data of the femur and tibia during ACL reconstruction.

Knee cinematics

Eligibility Criteria

• Age: 18 Years - 40 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Patient, male or female, aged between 18 and 40
• Patient eligible for ACL and LAL reconstruction
• Patient who is member of or covered by a social security scheme
• Patient who speaks French and has signed an informed consent form

You may not qualify if:

• Patient with a contraindication to MRI
• Patient with osteoarthritis of the joint
• Patient with a BMI \> 30
• Patient with history of trauma or previous knee surgery
• Patient with knee trauma other than a sprain
• Patient under legal guardianship: an adult under guardianship, curatorship or other legal protection, or deprived of liberty by judicial or administrative order
• Pregnant or breastfeeding woman

Sponsors & Collaborators

• GCS Ramsay Santé pour l'Enseignement et la Recherche: lead

Study Sites (1)

Hôpital Privé Jean Mermoz

Lyon, 69008, France

Location

MeSH Terms

Conditions

Anterior Cruciate Ligament Injuries

Condition Hierarchy (Ancestors)

Knee Injuries; Leg Injuries; Wounds and Injuries

Central Study Contacts

Bertrand SONNERY-COTTET

CONTACT

+ 33 4 37 53 00 22; sonnerycottet@aol.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: BASIC SCIENCE
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 13, 2026
• First Posted: June 18, 2026
• Study Start (Estimated): July 1, 2027
• Primary Completion (Estimated): March 1, 2028
• Study Completion (Estimated): March 1, 2028
• Last Updated: June 18, 2026

Record last verified: 2026-06

Locations

FR (1)