NCT07655557

Brief Summary

This is a pilot randomized controlled trial of a sexual health communication skills training multimedia intervention (Starting the Conversation \[STC\] adapted for patients with prostate cancer \[PCa\]) to improve patients' ability to communicate with providers about their sexual health concerns during PCa care compared to a time and attention control arm.

Trial Health

63
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
100

participants targeted

Target at P50-P75 for not_applicable prostate-cancer

Timeline
27mo left

Started Aug 2026

Geographic Reach
1 country

1 active site

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

June 11, 2026

Completed
7 days until next milestone

First Posted

Study publicly available on registry

June 18, 2026

Completed
1 month until next milestone

Study Start

First participant enrolled

August 1, 2026

Completed
2.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 31, 2028

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 31, 2028

Last Updated

July 1, 2026

Status Verified

June 1, 2026

Enrollment Period

2.3 years

First QC Date

June 11, 2026

Last Update Submit

June 29, 2026

Conditions

Keywords

Prostate CancerSexual HealthHealth Communication

Outcome Measures

Primary Outcomes (12)

  • Eligibility rate

    Proportion of screened individuals who are eligible

    Baseline

  • Enrollment rate

    Proportion of eligible individuals who enroll

    Baseline

  • Retention rate

    Proportion of enrolled participants who are not lost to follow-up

    Up to Month 2 Follow-Up

  • Assessment process

    Proportion of participants who completed intervention and assessments

    Up to Month 2 Follow-Up

  • Feasibility of Intervention Measure (FIM)

    FIM is a validated 4-item scale designed to evaluate whether a specific intervention or practice can be successfully implemented and carried out within a given setting. Each item is rated on a scale from 1-5; the total score is the average of the responses and ranges from 1-5; higher scores indicate greater feasibility.

    Post-Appointment (Day 1)

  • Acceptability of Intervention Measure (AIM)

    AIM is a validated 4-item scale used in implementation research to assess stakeholders' perception that a new program, treatment, or practice is agreeable and satisfactory. Each item is rated on a scale from 1-5; the total score is the average of the responses and ranges from 1-5; a higher overall average indicates a greater level of acceptability for the intervention.

    Post-Appointment (Day 1)

  • Intervention Appropriateness Measure (IAM)

    The Intervention Appropriateness Measure (IAM) is a validated, 4-item tool used in implementation science to assess the perceived fit, relevance, and suitability of an intervention. Each item is rated on scale from 1-5; the total score is the average of responses and ranges from 1-5; higher scores indicate greater appropriateness.

    Post-Appointment (Day 1)

  • Number of patients who raised a sexual health topic during clinic visit

    Post-Appointment (Day 1)

  • Number of patients who discussed sexual health concerns during clinic visit

    Post-Appointment (Day 1)

  • Number of patients who asked a sexual health question during clinic visit

    Post-Appointment (Day 1)

  • Self Efficacy - Talking about Sexual Health

    Self-efficacy for talking about sexual health with a healthcare provider, scored from 0-10. Higher scores indicate greater self-efficacy.

    Baseline, Post-Appointment (Day 1), Month 2 Follow-Up

  • Self Efficacy - Asking about Sexual Health

    Self-efficacy for asking a healthcare provider about sexual health, scored from 0-10. Higher scores indicate greater self-efficacy.

    Baseline, Post-Appointment (Day 1), Month 2 Follow-Up

Secondary Outcomes (1)

  • PROMIS Sexual Function and Satisfaction Measure (PROMIS SexFS v2.0)

    Baseline, Post-Appointment (Day 1), Month 2 Follow-Up

Study Arms (2)

Exposure to STC Intervention

EXPERIMENTAL

Participants will receive a multimedia intervention focused on teaching communication skills to help patients with prostate cancer discuss their sexual health concerns with their healthcare providers.

Behavioral: Starting the Conversation (STC)

Control Arm

ACTIVE COMPARATOR

The control arm will be exposed to a 2-page supportive care resource guide, as well as a video slideshow and pamphlet on diet, sleep, and exercise for patients with prostate cancer.

Behavioral: Time and Attention

Interventions

20-minute slideshow, 5-page workbook, 2-page supportive care resource guide focused on sexual health and teaching communication skills to help patients with prostate cancer discuss their sexual health concerns with their healthcare providers.

Exposure to STC Intervention

2-page supportive care resource guide, as well as a 20-minute video slideshow and 5-page pamphlet on diet, sleep, and exercise for patients with prostate cancer.

Control Arm

Eligibility Criteria

Age18 Years+
Sexmale
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Adult male with PCa at least 18 years of age
  • Speak English
  • Reside in the U.S.
  • Have internet/web access, and
  • Report current bother due to sexual dysfunction
  • Capacity and willingness to provide consent
  • Have an appointment with a PCa provider at NYU Langone Health during the study accrual period

You may not qualify if:

  • Individual with impaired decision-making capacity.
  • Participation in another part of this study (prior aim)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

NYU Langone Health

New York, New York, 10016, United States

Location

MeSH Terms

Conditions

Prostatic Neoplasms

Interventions

Time

Condition Hierarchy (Ancestors)

Genital Neoplasms, MaleUrogenital NeoplasmsNeoplasms by SiteNeoplasmsGenital Diseases, MaleGenital DiseasesUrogenital DiseasesProstatic DiseasesMale Urogenital Diseases

Intervention Hierarchy (Ancestors)

Physical Phenomena

Study Officials

  • Natasha Gupta, MD

    NYU Langone Health

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 11, 2026

First Posted

June 18, 2026

Study Start

August 1, 2026

Primary Completion (Estimated)

October 31, 2028

Study Completion (Estimated)

October 31, 2028

Last Updated

July 1, 2026

Record last verified: 2026-06

Data Sharing

IPD Sharing
Will share

The de-identified participant data from the final research dataset will be shared upon reasonable request beginning 9 to 36 months after publication or as required by a condition of awards or supporting agreements, provided the requesting investigator executes a data use agreement with NYU Langone Health. Datasets that can be shared will be deposited in open ICPSR. The protocol and statistical analysis plan will be posted on Clinicaltrials.gov only as required by federal regulation or supporting awards and agreements.

Shared Documents
STUDY PROTOCOL, SAP
Time Frame
Beginning 9 months and ending 36 months following article publication or as required by a condition of awards and agreements supporting the research.
Access Criteria
Datasets that can be shared will be deposited in open ICPSR.

Locations