NCT07654309

Brief Summary

  • To compare the effectiveness of in clinic rehabilitation versus tele rehabilitation in improving knee function in women diagnosed with knee OA.
  • To assess the impact of both rehabilitation approaches on improving strength.
  • To evaluate the effects of in-clinic and tele-rehabilitation on pain reduction in women with knee osteoarthritis.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
26

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Apr 2026

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 1, 2026

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 10, 2026

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 10, 2026

Completed
3 days until next milestone

First Submitted

Initial submission to the registry

June 13, 2026

Completed
4 days until next milestone

First Posted

Study publicly available on registry

June 17, 2026

Completed
Last Updated

June 17, 2026

Status Verified

February 1, 2026

Enrollment Period

2 months

First QC Date

June 13, 2026

Last Update Submit

June 13, 2026

Conditions

Total Knee Replacement

Keywords

Knee FunctionMuscle StrengthPain

Outcome Measures

Primary Outcomes (3)

  • WOMAC to assess knee function

    The WOMAC (Western Ontario and McMaster Universities Osteoarthritis Index) is a widely used, self-administered 24-item questionnaire designed to evaluate pain, joint stiffness, and physical function in patients with knee or hip osteoarthritis. It measures these three dimensions to assess disease severity and treatment outcomes.

    6 Weeks

  • MMT to assess knee muscle strength

    Manual Muscle Testing (MMT) is a generally valid and reliable tool for assessing muscle strength in patients with neuromusculoskeletal dysfunction, demonstrating good consistency, particularly in clinical settings with trained examiners. It is widely used for grading muscle strength (0-5 scale), though it has limited sensitivity in detecting small strength changes and may have a ceiling effect for high-functioning individuals.

    6 Weeks

  • VAS to assess pain

    The visual analog scale (VAS) is a validated, subjective measure for acute and chronic pain. Scores are recorded by making a handwritten mark on a 10-cm line that represents a continuum between "no pain" and "worst pain."

    6 Weeks

Study Arms (2)

In-Clinic Rehabilitation

EXPERIMENTAL

Hot pack (for 15 minutes) Strengthening Exercises 1. Quadriceps Sets - 3 Sets of 10 Reps 2. Straight Leg Raise (SLR) - 3 Set of 10 Reps 3. Mini Squats (Wall-Supported) - 3 Sets of 10 Reps 4. Hamstring Curls (Standing or Prone) - Reps: 3 sets of 10 Reps - Add resistance band if tolerated 5. Seated Knee Extension (With or Without Weight) - 3 sets of 10 Reps -18 sessions for six weeks.

Other: In-Clinic Rehabilitation

Tele-Rehabilitation

EXPERIMENTAL

Hot pack (for 15 minutes) Strengthening Exercises 1. Quadriceps Sets - 3 Sets of 10 Reps 2. Straight Leg Raise (SLR) - 3 Set of 10 Reps 3. Mini Squats (Wall-Supported) - 3 Sets of 10 Reps 4. Hamstring Curls (Standing or Prone) - Reps: 3 sets of 10 Reps - Add resistance band if tolerated 5. Seated Knee Extension (With or Without Weight) - 3 sets of 10 Reps -18 sessions for six weeks.

Other: Tele-Rehabilitaion

Interventions

In-Clinic RehabilitationOTHER

Hot Pack \& Strengthening Exercises

In-Clinic Rehabilitation
Tele-RehabilitaionOTHER

Hot Pack \& Strengthening Exercises

Tele-Rehabilitation

Eligibility Criteria

Age40 Years - 60 Years
Sexfemale(Gender-based eligibility)
Gender Eligibility DetailsBiologically identified.
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Only female participant
  • Age 40 to 60 years
  • Radiographically confirmed OA (Grade II or III)
  • Self-limitation in walking, climbing or ADLs
  • Access to smartphone, tablet, or computer with internet

You may not qualify if:

  • Advanced OA (G IV)
  • Other joint disorder
  • Recent surgeries
  • Pregnancy
  • Swelling and morning stiffness more than 30 min

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

THQ Hospital Dargai

Dargai, KPK, 23060, Pakistan

Location

MeSH Terms

Conditions

Pain

Condition Hierarchy (Ancestors)

Neurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Ayesha Sadiq, MSPT (OMPT)

    Riphah International University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
OTHER
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 13, 2026

First Posted

June 17, 2026

Study Start

April 1, 2026

Primary Completion

June 10, 2026

Study Completion

June 10, 2026

Last Updated

June 17, 2026

Record last verified: 2026-02

Data Sharing

IPD Sharing
Will not share

Locations

PA(1)