NCT07654205

Brief Summary

The primary goal of this clinical trial is to test if a smartphone-based intervention is feasible \& acceptable among young adults with ADHD who also engage in risky drinking behaviors. A secondary aim is to test preliminary intervention efficacy. The main questions it aims to answer are: Is the smartphone intervention feasible \& acceptable for participants (e.g., are they responding regularly, is there a low level of burden reported)? Does the smartphone intervention improve symptom awareness, inhibitory control, and problematic alcohol use? Participants will: Attend a virtual baseline visit to assess ADHD, alcohol use, and other life experiences. Complete either the TIPS smartphone intervention or a control smartphone protocol over the course of 31-days, starting the first Friday after the baseline visit. Attend a virtual follow-up visit, where many of the same questions from the baseline visit will be asked again.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
70

participants targeted

Target at P50-P75 for not_applicable

Timeline
10mo left

Started Jun 2026

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress5%
Jun 2026May 2027

Study Start

First participant enrolled

June 1, 2026

Completed
11 days until next milestone

First Submitted

Initial submission to the registry

June 12, 2026

Completed
5 days until next milestone

First Posted

Study publicly available on registry

June 17, 2026

Completed
9 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2027

Expected
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2027

Last Updated

June 17, 2026

Status Verified

June 1, 2026

Enrollment Period

9 months

First QC Date

June 12, 2026

Last Update Submit

June 12, 2026

Conditions

Outcome Measures

Primary Outcomes (2)

  • Average Completion Rate

    Completion rate will be defined as number of surveys completed out of the 124 that will be sent during the 31-day smartphone intervention period. 4 surveys will be sent every day. An average completion rate of 80% in the intervention group would indicate good feasibility.

    Enrollment to Completion of 31-Day Intervention Period

  • Average mHealth App Usability Questionnaire (MAUQ) Rating

    The usability of the smartphone intervention will be assessed using the 18-item mHealth App Usability Questionnaire (MAUQ), rated from 1-disagree to 7-agree, with an average of at least 5 indicating good usability.

    Within 1 month of intervention completion

Secondary Outcomes (3)

  • Change in past-month average alcohol quantity

    Enrollment to Completion of 31-Day Intervention Period,

  • Change in number of past-month binge-drinking episodes

    Enrollment to Completion of 31-Day Intervention Period

  • Change in number of past-month alcohol problems reported on the Young Adult Alcohol Consequence Questionnaire

    Enrollment to Completion of 31-Day Intervention Period

Other Outcomes (5)

  • Change in inhibitory control

    Enrollment to Completion of 31-Day Intervention Period

  • Change in awareness

    Enrollment to Completion of 31-Day Intervention Period

  • Change in objectively measured inhibitory control

    Enrollment to Completion of 31-Day Intervention Period

  • +2 more other outcomes

Study Arms (2)

Intervention Arm

EXPERIMENTAL

Participants in this arm will be randomly assigned to the Experimental condition of the smartphone portion.

Device: Ecological Momentary Assessment for ADHD and Substance Use - Intervention Group

Control Arm

SHAM COMPARATOR

Participants in this arm will be randomly assigned to the Control condition of the smartphone portion.

Device: Ecological Momentary Assessment for ADHD & Substance Use - Control Group

Interventions

Participants will rate their ADHD symptoms and impairment 4 times daily. Feedback on changes in ADHD symptoms will be provided visually via a graph at each prompt. They will also be texted suggestions following each survey to try behavioral strategies intended to help with their inhibitory control ADHD symptoms and related problems, with a particular focus on alcohol use and problems).

Intervention Arm

Participants will receive 4 prompts per day in the same time windows as participants in the intervention group. However, participants in the control conditions will not be given the 3 TIPS intervention components (symptom monitoring, symptom feedback, and tailored strategy suggestions) and instead will report about their drinking behaviors. They will also answer several "neutral" questionnaires that have been designed by the study team to keep intervention prompt length similar between groups.

Control Arm

Eligibility Criteria

Age18 Years - 25 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Age 18-25
  • Current diagnosis of Attention Deficit/Hyperactivity Disorder-Combined Type according to the Diagnostic and Statistical Manual of Mental Disorders - Fifth Edition (DSM 5)
  • Drinks at least 4 (for females) / 5 (for males) alcoholic drinks in a single drinking session at least once per week
  • Owns a smartphone
  • Reads and understands English

You may not qualify if:

  • Currently in high school
  • Actively in treatment for Alcohol Use Disorder
  • Alcohol use disorder-severe

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Pittsburgh

Pittsburgh, Pennsylvania, 15213, United States

RECRUITING

Related Publications (1)

  • Kennedy TM, Lee CM, Molina BSG, Pedersen SL. From Assessment to Intervention: Leveraging Ecological Momentary Assessment (EMA) to Develop a Personalized mobile-health (mHealth) Ecological Momentary Intervention (EMI) for Young Adults With ADHD and High-Risk Alcohol Use. J Stud Alcohol Drugs. 2026 Jan;87(1):34-53. doi: 10.15288/jsad.24-00449. Epub 2025 Aug 29.

    PMID: 40880228BACKGROUND

MeSH Terms

Conditions

Attention Deficit Disorder with HyperactivityAlcohol Drinking

Condition Hierarchy (Ancestors)

Attention Deficit and Disruptive Behavior DisordersNeurodevelopmental DisordersMental DisordersDrinking BehaviorBehavior

Study Officials

  • Traci Kennedy, PhD.

    University of Pittsburgh

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Traci Kennedy, PhD

CONTACT

Aiden Williard, B.S.

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
TRIPLE
Who Masked
PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
OTHER
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Assistant Professor

Study Record Dates

First Submitted

June 12, 2026

First Posted

June 17, 2026

Study Start

June 1, 2026

Primary Completion (Estimated)

March 1, 2027

Study Completion (Estimated)

May 1, 2027

Last Updated

June 17, 2026

Record last verified: 2026-06

Data Sharing

IPD Sharing
Will share

All collected IPD will be shared with the National Institute on Alcohol Abuse and Alcoholism Data Archive (NIAAADA). Analytic code may be shared on an open science platform at the time of publication of results.

Shared Documents
ANALYTIC CODE
Time Frame
Data will be uploaded to NIAAADA 6 months after data collection begins with no planned end date.
Access Criteria
Investigators who obtain permission to access this data in NIAAADA will have access to the IPD.
More information

Locations