Effect of Antigravity Treadmill Training on Cardiorespiratory Fitness and Lower Limb Function in Incomplete Spinal Cord Injury

NCT07653529 | Not Yet Recruiting DMC

• 1 other identifier: Antigravity Treadmill SCI
• Study Type: interventional
• Target: 60
• Locations: 0 countries
• Sites: N/A

Brief Summary

This study aims to investigate the effect of locomotor training using an antigravity treadmill on cardiorespiratory fitness and lower limb function in patients with incomplete spinal cord injury.

Conditions

Incomplete Spinal Cord Injury (SCI)

Outcome Measures

Primary Outcomes (2)

• Cardiorespiratory fitness

  Cardiopulmonary fitness will be measured by Cardiopulmonary Exercise Testing (CPET) to assess the integrated function of the cardiovascular, pulmonary, and muscular systems during exercise. The gold-standard parameter obtained from CPET is: VO₂max VO₂max: Maximum rate of oxygen consumption achieved during maximal exercise. Units: mL/kg/min

  At base line and 12 weeks

• Lower Limb Function

  Lower limb function will be measured by 10-Meter Walk Test (10MWT) is a simple and reliable measure of walking speed, Assesses: Gait speed Procedure Mark a 10-meter walkway. The patient will walks at: Comfortable/self-selected speed (usual gait speed) Walking Speed (m/s)= Distance (m) /Time (s)

  At base line and 12 weeks

Study Arms (2)

Study Group

ACTIVE COMPARATOR

Antigravity Treadmill Training: Participants will undergo locomotor training for 30-45 minutes per session, three sessions per week, for 12 weeks. The training protocol will include: * Warm-up for 5-10 minutes * Walking training with partial body-weight support * Progressive increase in treadmill speed according to tolerance * Gradual reduction of body-weight support * Cool-down period for 5 minutes

Device: Antigravity Treadmill for gait training; Other: gait training and balance exercise

Control group

ACTIVE COMPARATOR

Thirty patients with incomplete spinal cord injury will receive gait training between parallel bar and balance exercise

Other: gait training and balance exercise

Interventions

Antigravity Treadmill for gait training DEVICE

Antigravity treadmill for gait training

Study Group

gait training and balance exercise OTHER

gait training between Parallel bar Balance Exercise

Control group; Study Group

Eligibility Criteria

• Age: 40 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Incomplete spinal cord injury (ASIA C or D)
• Injury duration more than 3 months
• Ability to stand with or without assistance
• Medically stable condition

You may not qualify if:

• Complete spinal cord injury
• Severe cardiopulmonary disorders
• Severe osteoporosis or fractures
• Severe cognitive impairment
• Other neurological disorders affecting gait

Sponsors & Collaborators

• Middle East University: lead

Central Study Contacts

Saher Lotfy Elgayar, phd

CONTACT

00962786757649; selgayar@meu.edu.jo

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor of Physiotherapy

Study Record Dates

• First Submitted: May 20, 2026
• First Posted: June 17, 2026
• Study Start: June 12, 2026
• Primary Completion (Estimated): October 12, 2026
• Study Completion (Estimated): December 15, 2026
• Last Updated: June 17, 2026

Record last verified: 2026-06

Data Sharing

• IPD Sharing: Will not share