Relationship Between Genitourinary and Respiratory Symptoms in Postmanopause

NCT07651566 | Completed

• 1 other identifier: 02.06.26
• Study Type: observational
• Target: 28
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this study is to evaluate the relationship between genitourinary system symptoms and respiratory function and respiratory muscle strength in postmenopausal women.

Conditions

Menopause

Keywords

menopause; women; respiratory function; genitourinary function

Outcome Measures

Primary Outcomes (4)

• Bristol Female Lower Urinary Tract Symptoms Index (BUTSI)

  The BUTSI, for which a Turkish validity and reliability study has been conducted, consists of five sections evaluating storage symptoms; voiding symptoms ; urinary incontinence ; sexual function ; and quality of life The maximum total score is 60.A higher total score on the scale indicates a more negative impact on sexual life and quality of life, and more severe lower urinary tract symptoms.

  at baseline

• Postmenopausal Sexuality Questionnaire (PSQ)

  The MSCA, for which Turkish validity and reliability studies have been conducted, consists of a total of 36 items and nine sub-dimensions.The maximum total score is 100. A score of zero indicates the worst sexual function, while a score of 100 indicates the best sexual function (0-100).

  at baseline

• Respiratory function

  The evaluation was performed using a Cosmed Pony FX brand spirometer, in accordance with the criteria.A forced vital capacity maneuver test was administered to assess the respiratory function of the participants. During the forced vital capacity maneuver, the participant was asked to take a deep breath and, when they could no longer breathe, to forcefully, quickly, and for an extended period exhale all the air from their lungs, then take another deep breath. As a result of this test, forced vital capacity (FVC), forced expiratory volume in 1 second (FEV1), FEV1/FVC ratio, and peak airflow rate (PEF) values were obtained and recorded.

  at baseline.

• respiratory muscle strength

  The evaluation was performed using a Cosmed Pony FX brand spirometer. Maximum inspiratory pressure (MIP) and maximum expiratory pressure (MEP) tests were performed to assess the strength of the respiratory muscles. For the MIP test, the participant was asked to first completely exhale the air from their lungs, followed by a deep, rapid, and forceful full breath; for the MEP test, the participant was asked to first completely fill their lungs with air, followed by a rapid and forceful full exhale. MIP and MEP values were used as percentages of the expected values for gender and age, and Black and Hyatt equations were used when interpreting the values.

  at baseline.

Study Arms (1)

Women in Postmenopausal Period

All women who are postmenopausal and meet the participation criteria.

Eligibility Criteria

• Age: 50 Years - 64 Years
• Gender Eligibility Details: postmenopausal women
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

All women who are postmenopausal and meet the participation criteria.

You may qualify if:

• being between 50-64 years of age,
• having passed menopause no more than eight years ago,
• having experienced at least one pregnancy,
• being literate;

You may not qualify if:

• having received/currently receiving hormone replacement therapy,
• having any respiratory system disorder;
• having a serious chronic and/or metabolic disorder that may affect the outcome of the study;
• having cooperation problems.

Sponsors & Collaborators

• Halic University: lead

Study Sites (1)

Halic University

Istanbul, Turkey (Türkiye)

Location

Related Publications (2)

• Kurne HG, Akbayrak T. The validity and reliability of the Turkish version of the Postmenopause Sexuality Questionnaire. Int J Gynaecol Obstet. 2024 Apr;165(1):188-193. doi: 10.1002/ijgo.15293. Epub 2023 Dec 12.

  PMID: 38084782 RESULT

• Sarmento ACA, Costa APF, Vieira-Baptista P, Giraldo PC, Eleuterio J Jr, Goncalves AK. Genitourinary Syndrome of Menopause: Epidemiology, Physiopathology, Clinical Manifestation and Diagnostic. Front Reprod Health. 2021 Nov 15;3:779398. doi: 10.3389/frph.2021.779398. eCollection 2021.

  PMID: 36304000 RESULT

Related Links

• Related Info

MeSH Terms

Conditions

Respiratory Aspiration

Condition Hierarchy (Ancestors)

Respiration Disorders; Respiratory Tract Diseases; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• Duygu ŞAHİN, PT, PhD.

  Halic University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Target Duration: 1 Day
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 8, 2026
• First Posted: June 16, 2026
• Study Start: May 1, 2025
• Primary Completion: May 1, 2025
• Study Completion: March 1, 2026
• Last Updated: June 16, 2026

Record last verified: 2026-06

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)