NCT07648355

Brief Summary

This is a prospective, single-site, two-surgeon, single-arm, observational study evaluating the Clareon TruPlus IOL. Subjects will be assessed up to 3 months post-operatively. Clinical evaluations will include refractive outcomes, visual acuity, and administration of the IOLSAT Questionnaire.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
40

participants targeted

Target at P25-P50 for all trials

Timeline
13mo left

Started Jun 2026

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress3%
Jun 2026Jul 2027

Study Start

First participant enrolled

June 2, 2026

Completed
2 days until next milestone

First Submitted

Initial submission to the registry

June 4, 2026

Completed
11 days until next milestone

First Posted

Study publicly available on registry

June 15, 2026

Completed
1.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 11, 2027

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 11, 2027

Last Updated

June 15, 2026

Status Verified

June 1, 2026

Enrollment Period

1.1 years

First QC Date

June 4, 2026

Last Update Submit

June 9, 2026

Conditions

Outcome Measures

Primary Outcomes (1)

  • Binocular photopic DCIVA

    Measured using a standardized ETDRS chart at 66cm.

    3 months postoperatively

Secondary Outcomes (1)

  • Binocular photopic CDVA

    3 months postoperatively

Other Outcomes (13)

  • Binocular photopic DCNVA

    3 months postoperatively

  • Binocular uncorrected distance visual acuity UDVA (4m)

    3 months postoperatively

  • Binocular photopic uncorrected intermediate visual acuity UIVA (66cm)

    3 months postoperatively

  • +10 more other outcomes

Study Arms (1)

Clareon TruPlus

Device: Clareon TruPlus

Interventions

Clareon TruPlus

Clareon TruPlus

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Adults over 40 years undergoing age-related cataract surgery with expected visual outcomes of 20/25 or better.

You may qualify if:

  • Willing and able to understand and sign informed consent.
  • Adult patients (\>40 years old) undergoing age-related cataract surgery with expected best-corrected visual outcomes of 20/25 or better in both eyes pre-operatively as determined by surgeon and with regular corneal astigmatism correctable to less than 0.75 diopters post-operatively with no more than a T6 toric power IOL.
  • Normal ocular findings aside from cataract and mild dry eye.

You may not qualify if:

  • Subjects targeted for monovision.
  • Moderate-severe corneal pathology, irregular astigmatism, preexisting macular disease and other retinal degenerative diseases, diabetic retinopathy that is expected to cause future vision loss, glaucoma, severe dry eye disease, nystagmus, strabismus, amblyopia, zonular laxity or dehiscence, pseudoexfoliation.
  • Previous history of any ocular surgery including LASIK (excluding minor lid procedures).
  • Patients with irregular astigmatism/topography, corneal dystrophies, and pupil abnormalities.
  • Participation in another clinical study that could interfere with the results.
  • Any active ocular infection or inflammation.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Ovo Lasik + Lens

Saint Louis Park, Minnesota, 55416, United States

RECRUITING

MeSH Terms

Conditions

Cataract

Condition Hierarchy (Ancestors)

Lens DiseasesEye Diseases

Study Officials

  • Martha Whiting, MD

    OVO Lasik and Lens LLC

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 4, 2026

First Posted

June 15, 2026

Study Start

June 2, 2026

Primary Completion (Estimated)

July 11, 2027

Study Completion (Estimated)

July 11, 2027

Last Updated

June 15, 2026

Record last verified: 2026-06

Data Sharing

IPD Sharing
Will not share

Locations