Longitudinal Evaluation of Preoperative eHealth Literacy and Nutritional Index on Early Functional Recovery After Fragility Fractures

NCT07646756 | Completed

• 1 other identifier: 2022-R-184
• Study Type: observational
• Target: 353
• Locations: 1 country
• Sites: 1

Brief Summary

The integration of digital technologies into chronic disease rehabilitation has transformed people care, yet the specific impact of electronic health literacy on early functional outcomes in fragility fracture people remains underexplored. This study investigates the association between preoperative eHealth literacy and both preoperative and early postoperative functional outcomes in people with fragility fractures.

Conditions

Fragility Fracture

Outcome Measures

Primary Outcomes (4)

• Barthel Index

  Barthel Index (BI) is widely used to quantify activities of daily living and is sensitive to short-term changes during hospitalization. A low BI at discharge limits the effectiveness of rehabilitation and is associated with poor prognosis. The lowest score on this scale is 0, and the highest score is 100.

  At baseline, 3 days postoperatively, 7 days postoperatively and 30 days postoperatively data on Barthel Index.

• EQ-5D-5L

  EQ-5D is a health-related quality of life (HRQoL) questionnaire widely used in economic, clinical, and population health studies. The EQ-5D descriptive system comprises five dimensions: mobility, self-care, usual activities, pain/discomfort and anxiety/depression. It has two versions, a three-level EQ-5D (EQ-5D-3L) and a five-level EQ-5D (EQ-5D-5L). Each dimension of the EQ-5D-3L consists of 3 levels: no difficulty at all, some difficulty, and extreme difficulty.

  At baseline, 3 days postoperatively, 7 days postoperatively and 30 days postoperatively data on EQ-5D-5L.

• PNI

  The PNI was derived using the formula: 10 × serum albumin (g/dL) + 0.005 × lymphocyte count (/mm3). Serum albumin \< 4.0 g/dL = 1 point, ≥4.0 g/dL = 0 points and LMR \< 4.44 = 1 point, ≥4.44 = 0 points. The total PNI varied from 0 to 4, higher values reflect a more favorable nutritional and inflammatory profile.

  At baseline, 3 days postoperatively, 7 days postoperatively and 30 days postoperatively data on PNI.

• EQ-VAS

  Participants rated their current health on a 100-point EQ visual analog scale (EQ VAS), ranging from "worst imaginable health state" (0) to "best imaginable health state" (100).

  At baseline, 3 days postoperatively, 7 days postoperatively and 30 days postoperatively data on EQ-VAS.

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

* People diagnosed with fragility fractures according to the clinical "Primary Osteoporosis Diagnosis and Treatment Guidelines (2022 Edition)"\[17\] and based on the clinical diagnosis； * People who have undergone conventional surgical treatment； * People who are conscious and able to communicate normally； ④ People who have provided informed consent and voluntarily participate in this study； ⑤ People aged ≥18 years.

You may qualify if:

• People diagnosed with fragility fractures according to the clinical "Primary Osteoporosis Diagnosis and Treatment Guidelines (2022 Edition)"\[17\] and based on the clinical diagnosis；
• People who have undergone conventional surgical treatment； ③ People who are conscious and able to communicate normally；
• ④ People who have provided informed consent and voluntarily participate in this study；
• ⑤ People aged ≥18 years.

You may not qualify if:

• Individuals with severe cognitive impairment;
• Pathological fractures caused by tumors or other reasons; ③ People with other severe diseases, such as cancer, severe cardiopulmonary diseases, etc., who are unable to cooperate; ④ Individuals currently participating in other research projects.

Sponsors & Collaborators

• Shandong University: lead

Study Sites (1)

Shandong University

Jinan, Shandong, 250000, China

Location

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 30 Days
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: May 22, 2026
• First Posted: June 15, 2026
• Study Start: September 1, 2022
• Primary Completion: June 1, 2025
• Study Completion: July 1, 2025
• Last Updated: June 15, 2026

Record last verified: 2026-06

Locations

CN (1)