NCT07645872

Brief Summary

The aim of the registry is to gather real-life data to evaluate the clinical performance and safety of medical devices in patients who have been treated with HIFU thank to the Focal One device for their prostate cancer.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
3,000

participants targeted

Target at P75+ for all trials

Timeline
58mo left

Started Feb 2023

Longer than P75 for all trials

Geographic Reach
1 country

5 active sites

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress41%
Feb 2023Apr 2031

Study Start

First participant enrolled

February 1, 2023

Completed
3.1 years until next milestone

First Submitted

Initial submission to the registry

March 5, 2026

Completed
3 months until next milestone

First Posted

Study publicly available on registry

June 12, 2026

Completed
4.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2031

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2031

Last Updated

June 12, 2026

Status Verified

June 1, 2026

Enrollment Period

8.2 years

First QC Date

March 5, 2026

Last Update Submit

June 10, 2026

Conditions

Outcome Measures

Primary Outcomes (1)

  • To monitor the safety of HIFU treatment with the Focal One in patients treated for prostate cancer.

    Safety will be assessed by collecting adverse events related to HIFU treatment.

    From HIFU treatment up to 5 years post-HIFU

Secondary Outcomes (4)

  • PSA values after HIFU treatment

    From HIFU treatment up to 5 years post-HIFU

  • Incidence of local recurrence detected by prostate MRI after HIFU treatment

    From HIFU treatment up to 5 years post-HIFU

  • Prostate biopsy results after HIFU treatment

    From HIFU treatment up to 5 years post-HIFU

  • To estimate the retreatment rate of patients treated with HIFU

    From HIFU treatment up to 5 years post-HIFU

Eligibility Criteria

Sexmale(Gender-based eligibility)
Gender Eligibility DetailsTo have a prostate
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients Being treated for prostate cancer with the Focal One device

You may qualify if:

  • Being treated for prostate cancer with the Focal One device
  • Patient does not object and consent\* to the collection of clinical data in the registry

You may not qualify if:

  • Patient deprived of liberty following a judicial or administrative decision
  • Patient under guardianship or curatorship \* if applicable according to local regulation

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (5)

Hôpital privé Aix en provence

Aix-en-Provence, 13080, France

RECRUITING

Clinique Saint vincent

Besançon, 25056, France

RECRUITING

Hôpital Civil Colmar

Colmar, 68000, France

RECRUITING

Hôpital Edouard Heriot

Lyon, 69000, France

RECRUITING

Clinique Nantes Atlantis

Nantes, 44000, France

RECRUITING

MeSH Terms

Conditions

Prostatic Neoplasms

Condition Hierarchy (Ancestors)

Genital Neoplasms, MaleUrogenital NeoplasmsNeoplasms by SiteNeoplasmsGenital Diseases, MaleGenital DiseasesUrogenital DiseasesProstatic DiseasesMale Urogenital Diseases

Central Study Contacts

Léa GUEDJ

CONTACT

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
OTHER
Target Duration
5 Years
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 5, 2026

First Posted

June 12, 2026

Study Start

February 1, 2023

Primary Completion (Estimated)

April 1, 2031

Study Completion (Estimated)

April 1, 2031

Last Updated

June 12, 2026

Record last verified: 2026-06

Data Sharing

IPD Sharing
Will not share

Locations