Osteopathic Manual Therapy Versus Ganglion Impar Block for Chronic Coccygodynia

NCT07642167 | Completed

• 2 other identifiers: COCCY-OMT-GIB-20252025/03-03
• Study Type: interventional
• Target: 100
• Locations: 1 country
• Sites: 2

Brief Summary

The goal of this clinical trial is to compare two treatment methods for chronic coccygodynia (tailbone pain) in adults. The study aims to determine which treatment provides better pain relief and functional improvement. The main questions it aims to answer are: Does osteopathic manual therapy reduce pain and disability in people with chronic coccygodynia? Does ganglion impar block reduce pain and disability in people with chronic coccygodynia? Which treatment provides more sustained improvement during follow-up? Researchers will compare osteopathic manual therapy with ganglion impar block to evaluate their effects on pain, function, quality of life, and patient satisfaction. Participants will: Be randomly assigned to one of the two treatment groups. Receive either osteopathic manual therapy or ganglion impar block. Complete pain, disability, neuropathic pain, and quality-of-life assessments before treatment and during follow-up visits. Attend follow-up evaluations at 3 weeks and 3 months after treatment.

Conditions

Chronic Coccygodynia

Keywords

Chronic Coccygodynia; Coccygodynia; Ganglion Impar Block; Osteopathic Manual Therapy; Chronic Pain; Functional Disability; Rehabilitation; Disability Evaluation; Numerical Rating Scale; Oswestry Disability Index; Randomized Controlled Trial; Pain Management

Outcome Measures

Primary Outcomes (1)

• Change in Oswestry Disability Index (ODI) Score

  Assessment of functional disability related to chronic coccygodynia using the Oswestry Disability Index.

  Baseline and 3 months

Secondary Outcomes (1)

• Change in Numeric Rating Scale (NRS) Pain Score

  Baseline, 3 weeks, and 3 months

Study Arms (2)

Osteopathic Manual Therapy

EXPERIMENTAL

Participants received a 6-week osteopathic manual therapy program including coccygeal mobilization, levator ani muscle techniques, myofascial release, and neural stretching exercises.

Procedure: Osteopathic Manual Therapy

Ganglion Impar Block

ACTIVE COMPARATOR

Participants received a fluoroscopy-guided ganglion impar block with local anesthetic and corticosteroid injection.

Procedure: Ganglion Impar Block

Interventions

Ganglion Impar Block PROCEDURE

A fluoroscopy-guided ganglion impar block performed with local anesthetic and corticosteroid injection for pain management in chronic coccygodynia.

Ganglion Impar Block

Osteopathic Manual Therapy PROCEDURE

A 6-week osteopathic manual therapy program including coccygeal mobilization, levator ani muscle techniques, myofascial release, and neural stretching exercises.

Osteopathic Manual Therapy

Eligibility Criteria

• Age: 18 Years - 75 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Age 18-75 years Chronic coccygodynia persisting for at least 3 months Unresponsive to previous conservative treatment Baseline NRS score ≥4 Baseline ODI score ≥20 Written informed consent

You may not qualify if:

• Acute coccygodynia Previous coccygeal or spinal surgery Malignancy Pelvic fracture Pregnancy Coagulation disorders Severe psychiatric disease Previous osteopathic manual therapy or ganglion impar block Structural pathology identified on MRI or dynamic radiography

Sponsors & Collaborators

• Atlas University: lead

Study Sites (2)

İstanbul atlas university

Istanbul, Istanbul, Turkey (Türkiye)

Location

İstanbul atlas university

Istanbul, Kadiköy, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Chronic Pain; Agnosia

Condition Hierarchy (Ancestors)

Pain; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Perceptual Disorders; Neurobehavioral Manifestations; Nervous System Diseases

Study Officials

• mert sancar, MD

  Istanbul Atlas University Faculty of Medicine

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Masking Details: Due to the nature of the interventions, participant and provider blinding was not feasible.
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: Participants with chronic coccygodynia were randomly assigned in a 1:1 ratio to either osteopathic manual therapy (OMT) or ganglion impar block (GIB). Outcomes were assessed at baseline, 3 weeks, and 3 months.

Study Record Dates

• First Submitted: June 8, 2026
• First Posted: June 11, 2026
• Study Start: August 28, 2025
• Primary Completion: March 12, 2026
• Study Completion: April 2, 2026
• Last Updated: June 11, 2026

Record last verified: 2025-09

Data Sharing

• IPD Sharing: Will not share

Locations

TU (2)