Non-Pharmacological Factors on Spinal Block Duration

NCT07638280 | Recruiting

• 1 other identifier: 2026.02.IRB.121
• Study Type: observational
• Target: 140
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this study is to evaluate the effects of non-pharmacological factors-such as age, sex, body mass index, paraspinal muscle mass, vertebral canal anatomy, patient positioning, and injection technique-on the duration of sensory and motor block in patients undergoing spinal anesthesia, and to investigate the potential relationships between these factors and block duration.

Conditions

Paraspinal Muscle Mass and Spinal Anaesthesia

Keywords

anaesthesia; spinal anaesthesia; ultrasound

Outcome Measures

Primary Outcomes (1)

• Paraspinal mass measurement with ultrasound.

  Ultrasonographic measurement of paraspinal muscle thickness (cm) and its association with duration of spinal block will be investigated.

  Pre-operative

Secondary Outcomes (1)

• The spread of the spinal block

  Perioperative/Periprocedural

Interventions

spinal anaesthesia PROCEDURE

Patients who will undergo surgery required spinal anaesthesia

Eligibility Criteria

• Age: 18 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Patients aged 18-80 years, male and female, classified as ASA physical status I-III, and scheduled for elective lower abdominal surgery.

You may qualify if:

• Patients aged 18-80 years
• ASA physical status I-III
• Patients scheduled for elective lower abdominal surgery.

You may not qualify if:

• Patient refusal to participate
• Coagulopathy
• Use of medications or substances known to impair coagulation
• Pregnancy, sepsis
• Shock
• Severe aortic or mitral regurgitation
• Peripheral vascular disease
• Increased intracranial pressure
• Mental disorders
• Spinal column deformity
• History of previous spinal surgery.

Sponsors & Collaborators

• Taksim Egitim ve Arastirma Hastanesi: lead

Study Sites (1)

Taksim Training and Research Hospital

Istanbul, 34000, Turkey (Türkiye)

RECRUITING

Related Publications (3)

• Kahveci M, Ugur L. The Effect of Injection Parameters on Drug Distribution for Spinal Anesthesia: A Numerical Approach. J Clin Med. 2025 Sep 3;14(17):6236. doi: 10.3390/jcm14176236.

  PMID: 40943995 RESULT

• Paliwal N, Khan IA. Exploring Variability in Spinal Anesthesia Levels Achieved During Cesarean Section Deliveries: A Narrative Review. Cureus. 2025 Jul 21;17(7):e88429. doi: 10.7759/cureus.88429. eCollection 2025 Jul.

  PMID: 40842780 RESULT

• Belavy DL, Armbrecht G, Felsenberg D. Real-time ultrasound measures of lumbar erector spinae and multifidus: reliability and comparison to magnetic resonance imaging. Physiol Meas. 2015 Nov;36(11):2285-99. doi: 10.1088/0967-3334/36/11/2285. Epub 2015 Oct 9.

  PMID: 26450474 RESULT

MeSH Terms

Interventions

Anesthesia, Spinal

Intervention Hierarchy (Ancestors)

Anesthesia, Conduction; Anesthesia; Anesthesia and Analgesia

Study Officials

• Leyla Sivacigil

  Taksim Training and Research Hospital

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Leyla Sivacigil, MD

CONTACT

905065983478; veralleyla@hotmail.com

Guray Demir, Proffesor

CONTACT

90 5052113989; guraydemir@gmail.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER GOV
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: April 20, 2026
• First Posted: June 10, 2026
• Study Start: June 16, 2026
• Primary Completion (Estimated): December 1, 2026
• Study Completion (Estimated): December 16, 2026
• Last Updated: June 23, 2026

Record last verified: 2026-04

Locations

TU (1)