An Study Looking at Percutaneous Coronary Intervention Outcomes for Octogenarians

NCT07633964 | Not Yet Recruiting

• 2 other identifiers: 25/085/GHT26/WM/0104
• Study Type: observational
• Target: 850
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this observational study is to understand the makeup of the participants aged 80 years and older who had stents fitted or balloon expansion of their heart arteries, otherwise known as percutaneous coronary intervention (PCI), at our hospital over a seven year period. The investigators will aim to describe the cohort with respect to their health conditions, age and frailty in addition to whether their procedure was planned or an emergency. The investigators will also look at the outcomes of these participants up to one year post procedure. The secondary aim is to look for associations between participant variables and their outcomes in hospital and at 1 year. The specific outcomes the investigators will look at are: inpatient complications and the incidence of heart attacks, strokes, unplanned PCI, cardiac rehospitalisation or death.

Conditions

Cardio Vascular Disease

Keywords

cardiovascular; octogenarian; frailty; SYNTAX; Percutaneous Coronary Intervention; calcification severity

Outcome Measures

Primary Outcomes (10)

• Myocardial infarction

  Number of participants who suffered a myocardial infarction post-procedure.

  1 year

• Unplanned revascularisation

  The number of participants who had unplanned revascularisation.

  1 year

• Cerebrovascular accident

  The number of participants who suffered a cerebrovascular accident

  1 year.

• Unplanned cardiac readmission

  The number of participants who had an unplanned readmission to the cardiac ward.

  1 year.

• Death

  Death from any cause.

  1 year

• Arterial complication

  The number of participants who suffered an inpatient arterial complication.

  1 year.

• Blood transfusion

  The number of participants who required an inpatient blood transfusion.

  1 year.

• Renal replacement therapy

  The number of participants who required inpatient renal replacement therapy.

  1 year.

• Gastrointestinal bleed

  The number of participants who suffered an upper gastrointestinal bleed.

  1 year

• Tamponade

  The number of participants who experienced an inpatient cardiac tamponade.

  1 year

Study Arms (1)

Octogenarians who had PCI between 2017-2023

Procedure: Percutaneous Coronary Intervention

Interventions

Percutaneous Coronary Intervention PROCEDURE

Percutaneous Coronary Intervention for example balloon angioplasty and balloon angioplasty with stent insertion.

Octogenarians who had PCI between 2017-2023

Eligibility Criteria

• Age: 80 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Participants who had PCI at our hospital trust between 1st January 2017 - 31st December 2023 and were aged 80 years and older.

You may qualify if:

• Participants who had PCI at our hospital trust between 1st January 2017 - 31st December 2023.

You may not qualify if:

• Participants with negative pressure wire studies (i.e. the lesion identified was not flow restricting).
• Participants had "failed PCI".
• Participants with significantly incomplete data despite thorough review of the electronic records.

Sponsors & Collaborators

• Gloucestershire Hospitals NHS Foundation Trust: lead

Study Sites (1)

Gloucestershire Hospitals NHS Foundation Trust

Gloucester, Gloucestershire, GL1 3NN, United Kingdom

Location

MeSH Terms

Conditions

Frailty

Interventions

Percutaneous Coronary Intervention

Condition Hierarchy (Ancestors)

Pathologic Processes; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Endovascular Procedures; Vascular Surgical Procedures; Cardiovascular Surgical Procedures; Surgical Procedures, Operative; Minimally Invasive Surgical Procedures

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Honorary Clinical Fellow

Study Record Dates

• First Submitted: May 25, 2026
• First Posted: June 8, 2026
• Study Start: June 1, 2026
• Primary Completion (Estimated): June 1, 2027
• Study Completion (Estimated): June 1, 2027
• Last Updated: June 8, 2026

Record last verified: 2026-06

Data Sharing

• IPD Sharing: Will not share

Locations

GB (1)