Moses 2.0 vs Magneto for HoLEP - a Randomized Controlled Trial
MOSES 2.0 vs Quanta Magneto 150 Holmium Laser for Holmium Laser Enucleation of the prostate-a Randomized Controlled Trial
1 other identifier
interventional
180
1 country
1
Brief Summary
The objective of this study is to compare the Magneto 150 holmium laser to the current MOSES 2.0 technology to see if there is a benefit in decreased hemostasis time intraoperatively.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable
Started Jun 2026
Typical duration for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
June 1, 2026
CompletedFirst Submitted
Initial submission to the registry
June 2, 2026
CompletedFirst Posted
Study publicly available on registry
June 8, 2026
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 1, 2027
ExpectedStudy Completion
Last participant's last visit for all outcomes
June 1, 2028
June 8, 2026
April 1, 2026
1 year
June 2, 2026
June 5, 2026
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Mean hemostasis time
Overall intraoperative hemostasis time
During surgery
Secondary Outcomes (3)
Mean (average) enucleation time
During surgery
Total operative time
During surgery
Hemostasis efficiency
During surgery
Study Arms (2)
Moses 2.0
ACTIVE COMPARATORHoLEP procedure performed using the Moses 2.0 holmium laser
Magneto 150
EXPERIMENTALHoLEP procedure performed using Magneto 150 holmium laser
Interventions
The HoLEP procedure will be performed using the Quanta Magneto 150 holmium laser
The HoLEP procedure will be performed using the Moses 2.0 holmium laser
Eligibility Criteria
You may qualify if:
- Undergoing HoLEP for the treatment of bothersome lower urinary tract symptoms
- Internet access and a device to complete postoperative questionnaires (smartphone, tablet, laptop or desktop computer)
You may not qualify if:
- Patients who lack decisional capacity
- Patients unable to read/speak English
- Patients who are on a blood thinner (anticoagulation medication)
- Patients who do not have internet access to complete postoperative surveys
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Cook Group Incorporatedcollaborator
- Northwestern Universitylead
Study Sites (1)
Northwestern University
Chicago, Illinois, 60611, United States
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Perry Xu, MD
Northwestern University
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Masking Details
- Participants will be randomized to undergo HoLEP with their surgeon using the MOSES 2.0 holmium laser or the Magneto 150 holmium laser. Participants will not know their randomization prior to procedure, but they will be able to find out at any time after the HoLEP procedure.
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Professor
Study Record Dates
First Submitted
June 2, 2026
First Posted
June 8, 2026
Study Start
June 1, 2026
Primary Completion (Estimated)
June 1, 2027
Study Completion (Estimated)
June 1, 2028
Last Updated
June 8, 2026
Record last verified: 2026-04
Data Sharing
- IPD Sharing
- Will not share