NCT07631962

Brief Summary

In this study, using a large retrospective cohort, the investigators evaluate the impact of RT on disease-free survival and overall survival of patients with BC. The aim is to determine the true role of radiotherapy in improving patient outcomes and to provide a basis for designing more precise treatment strategies in the future.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,030

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jan 1998

Longer than P75 for all trials

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 1998

Completed
10.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 1, 2008

Completed
16.9 years until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2025

Completed
1.4 years until next milestone

First Submitted

Initial submission to the registry

May 28, 2026

Completed
11 days until next milestone

First Posted

Study publicly available on registry

June 8, 2026

Completed
Last Updated

June 8, 2026

Status Verified

June 1, 2026

Enrollment Period

10.1 years

First QC Date

May 28, 2026

Last Update Submit

June 3, 2026

Conditions

RadiotherapyBreast Cancer

Outcome Measures

Primary Outcomes (1)

  • Survival

    25 years

Study Arms (2)

Breast Cancer Patients who underwent RT

Radiation: radiotherapy

Breast Cancer Patients who did not underwent RT

Interventions

radiotherapyRADIATION

Radiotherapy after BCS surgery in accordance to standard breast cancer guidelines

Breast Cancer Patients who underwent RT

Eligibility Criteria

Sexfemale(Gender-based eligibility)
Gender Eligibility DetailsFemales
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

BC patients diagnosed between January 1998 and February 2008 were identified from prospectively maintained breast cancer registries in the Motamed Breast Cancer Research in Tehran, Iran.

You may qualify if:

  • BC patients diagnosed between January 1998 and February 2008 in the Motamed Breast Cancer Research in Tehran, Iran.

You may not qualify if:

  • Male patients.
  • Patients with missing LPFS and OS information (zero encounter/follow-up).

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Breast Neoplasms

Interventions

Radiotherapy

Condition Hierarchy (Ancestors)

Neoplasms by SiteNeoplasmsBreast DiseasesSkin DiseasesSkin and Connective Tissue Diseases

Intervention Hierarchy (Ancestors)

Therapeutics

Study Design

Study Type
observational
Observational Model
CASE CROSSOVER
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Dr. Fereshteh Abbasvandi

Study Record Dates

First Submitted

May 28, 2026

First Posted

June 8, 2026

Study Start

January 1, 1998

Primary Completion

February 1, 2008

Study Completion

January 1, 2025

Last Updated

June 8, 2026

Record last verified: 2026-06