The Impact of Ultrasound Measurements in Predicting Difficult Airway on Videolaryngoscopy Success

NCT07628868 | Active Not Recruiting

• 1 other identifier: 2025/46
• Study Type: observational
• Target: 350
• Locations: 1 country
• Sites: 1

Brief Summary

In this preoperative observational study, the effect of preoperative ultrasonographic measurements on the success of videolaryngoscopy in predicting difficult airways was investigated; furthermore, the aim was to determine new cut-off values that can predict difficult intubation in videolaryngoscope use. In our study, it was tested that the use of videolaryngoscope significantly increased the success of intubation in patients who were assessed as having difficult airways with upper airway ultrasound measurements.

Conditions

Ultrasonography; Difficult Airway

Keywords

Difficult airway; Ultrasonography; Difficult laryngoscopy; Difficult mask ventilation

Outcome Measures

Primary Outcomes (1)

• Difficult videolaryngoscopic intubation

  Difficult videolaryngoscopic intubation will be assessed using the VIDIAC score, a scoring system specifically developed to quantify intubation difficulty during videolaryngoscopy.

  During videolaryngoscopy (periprocedural)

Secondary Outcomes (1)

• Difficult mask ventilation

  During ventilation (periprocedural)

Study Arms (1)

None (Orotracheal intubation will be performed using a videolaryngoscope in all patients)

Patients aged 18 years and older, classified as American Society of Anesthesiologists (ASA) physical status I-III, who will undergo surgery under general anesthesia requiring orotracheal intubation, will be included in this prospective observational study.

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients undergoing elective surgery under general anesthesia requiring endotracheal intubation

You may qualify if:

• Patients aged 18 years and older
• Patients undergoing elective surgery under general anesthesia requiring endotracheal intubation (ASA I-III)

You may not qualify if:

• Patients undergoing surgery under sedation or regional anesthesia
• Patients not planned for endotracheal intubation
• Patients with a history of difficult airway
• Patients with an acute respiratory tract infection
• Patients with congenital or acquired upper airway anomalies
• Patients with facial or maxillofacial tumors or fractures
• Patients with cervical spine fracture
• Patients with a history of cervical or craniofacial radiotherapy
• Patients with a tracheostomy
• Pregnant patients
• Patients who do not meet the required fasting period or who refuse to -participate in the study

Sponsors & Collaborators

• Bakirkoy Dr. Sadi Konuk Research and Training Hospital: lead

Study Sites (1)

SBÜ Bakırköy Dr. Sadi Konuk Eğitim ve Araştırma Hastanesi

Istanbul, Bakirköy, 34147, Turkey (Türkiye)

Location

Related Publications (5)

• Wu J, Dong J, Ding Y, Zheng J. Role of anterior neck soft tissue quantifications by ultrasound in predicting difficult laryngoscopy. Med Sci Monit. 2014 Nov 18;20:2343-50. doi: 10.12659/MSM.891037.

  PMID: 25403231 BACKGROUND

• Kheterpal S, Han R, Tremper KK, Shanks A, Tait AR, O'Reilly M, Ludwig TA. Incidence and predictors of difficult and impossible mask ventilation. Anesthesiology. 2006 Nov;105(5):885-91. doi: 10.1097/00000542-200611000-00007.

  PMID: 17065880 BACKGROUND

• Gomes SH, Simoes AM, Nunes AM, Pereira MV, Teoh WH, Costa PS, Kristensen MS, Teixeira PM, Pego JM. Useful Ultrasonographic Parameters to Predict Difficult Laryngoscopy and Difficult Tracheal Intubation-A Systematic Review and Meta-Analysis. Front Med (Lausanne). 2021 May 28;8:671658. doi: 10.3389/fmed.2021.671658. eCollection 2021.

  PMID: 34124099 BACKGROUND

• Kheterpal S, Martin L, Shanks AM, Tremper KK. Prediction and outcomes of impossible mask ventilation: a review of 50,000 anesthetics. Anesthesiology. 2009 Apr;110(4):891-7. doi: 10.1097/ALN.0b013e31819b5b87.

  PMID: 19293691 BACKGROUND

• Apfelbaum JL, Hagberg CA, Connis RT, Abdelmalak BB, Agarkar M, Dutton RP, Fiadjoe JE, Greif R, Klock PA, Mercier D, Myatra SN, O'Sullivan EP, Rosenblatt WH, Sorbello M, Tung A. 2022 American Society of Anesthesiologists Practice Guidelines for Management of the Difficult Airway. Anesthesiology. 2022 Jan 1;136(1):31-81. doi: 10.1097/ALN.0000000000004002.

  PMID: 34762729 BACKGROUND

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER GOV
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor, Principal Investigator

Study Record Dates

• First Submitted: December 15, 2025
• First Posted: June 5, 2026
• Study Start: December 21, 2025
• Primary Completion: June 10, 2026
• Study Completion: July 20, 2026
• Last Updated: June 5, 2026

Record last verified: 2026-06

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)