NCT07626632|Recruiting
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Sponsor study identifier
interventional
38
1 country
1
Study Start
August 1, 2026
Actual (reported)Primary Completion
October 20, 2026
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
Study Completion
November 13, 2026
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
This study aims to compare the effects of the Tyler Twist exercise versus traditional eccentric exercises on pain, grip strength, and functional outcomes in patients diagnosed with lateral epicondylalgia. The primary objective is to determine which intervention offers greater improvement in clinical symptoms and overall function over a defined treatment period.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
November 13, 2026
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
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Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
June 1, 2026
Actual (reported)June 4, 2026
Actual (reported)August 1, 2026
Actual (reported)October 20, 2026
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
November 13, 2026
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Numeric pain rate scale (NPRS) for pain
To determine the degree of pain that the patient will report, the Numeric Pain Rating Scale (NPRS) will be utilized. This scale consists of 11 points ranging from 0-10, where zero indicates no pain, five represents moderate pain intensity, and ten signifies severe pain intensity
6 weeks
Handheld dynamometer for grip strength:
For pain-free grip strength assessment, the patient's arm is positioned comfortably with the shoulder adducted and neutrally rotated, the elbow flexed to 90 degrees.20, the forearm in a neutral position, and the wrist in slight extension and ulnar deviation. The patient is instructed to squeeze as tightly as possible for 3-5 seconds, with multiple trials and an average of three repetitions recorded. A brief pause is provided between trials to prevent muscle fatigue. Hand-held dynamometers have been shown to have excellent internal validity and reliability, with reported values of 0.31-0.69 in the upper extremities
6 weeks
Patient-Rated Tennis Elbow Evaluation (PRTEE) for functional disability
The PRTEE questionnaire is one of the most widely-used outcome measures that appreciates elbow
6 weeks
The Tyler Twist is a specific eccentric exercise using the TheraBand FlexBar, designed to target the extensor carpi radialis brevis (ECRB), which is primarily involved in lateral epicondylalgia.
This protocol involves eccentric strengthening of the wrist extensor muscles (primarily ECRB)using a dumbbell (1-2 kg) or wrist cuff weight.
* Position: * The patient holds the FlexBar in both hands. * The affected arm is placed in front with the elbow extended and wrist in slight extension. * The unaffected hand grips the other end of the FlexBar. * Twisting Motion: 1. The patient uses the unaffected hand to twist the FlexBar into a taut position while the affected hand resists the motion (eccentric loading). 2. Once the FlexBar is twisted, the patient extends the arms in front and slowly untwists the bar with the affected wrist, creating a controlled eccentric contraction. 3. Emphasis is placed on slow, controlled movement (2-3 seconds for untwist). 4. 3 sets of 15 repetitions, once daily. 5. Progress to higher resistance FlexBars as tolerated (e.g., from red to green to blue). 6. Supervision during clinical visits (twice per week), rest is home-based
Ghurki Hospital Lahore
Lahore, Punjab Province, 54000, Pakistan
Cancela-Cilleruelo I, Rodriguez-Jimenez J, Fernandez-de-Las-Penas C, Cleland JA, Arias-Buria JL. Widespread Pressure Pain Hyperalgesia Is Not Associated With Morphological Changes of the Wrist Extensor Tendon in Unilateral Lateral Epicondylalgia: A Case-Control Study. Phys Ther. 2024 Sep 4;104(9):pzae075. doi: 10.1093/ptj/pzae075.
Karabinov V, Georgiev GP. Lateral epicondylitis: New trends and challenges in treatment. World J Orthop. 2022 Apr 18;13(4):354-364. doi: 10.5312/wjo.v13.i4.354. eCollection 2022 Apr 18.
Hira Shaukat, Mphill
Riphah International University
First Submitted
June 1, 2026
First Posted
June 4, 2026
Study Start
August 1, 2026
Actual (reported)Primary Completion
October 20, 2026
Estimated (date passed)* Position: * Patient seated with the forearm resting on a table, palm facing down, wrist hanging off the edge. * Elbow flexed to \~90 degrees. * Eccentric Movement: 0\. The patient uses the unaffected hand to assist the affected wrist into extension (starting position). 1. The affected wrist then slowly lowers the weight into flexion (eccentric contraction). 2. The cycle is repeated, focusing on slow movement (2-4 seconds lowering phase). 3. 3 sets of 10-15 reps, once daily. 4. Weight increased progressively based on pain-free performance. 5. Supervised sessions 2x/week; home exercise on other days
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This estimate has passed. The registry has not confirmed an actual date for this milestone.
Study Completion
November 13, 2026
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Last Updated
September 24, 2026
Record last verified: 2026-09
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