Bite Force and Occlusal Force Distribution Following Root Canal Treatment.

NCT07626372 | Not Yet Recruiting

• 1 other identifier: HREC-DCU 2025-206
• Study Type: observational
• Target: 70
• Locations: 1 country
• Sites: 1

Brief Summary

Understanding the changes in bite force and occlusal force distribution in ETT is clinically important, as it can directly influence tooth prognosis, guide restorative treatment planning, and impact the long-term survival of the treated tooth. Therefore, this study aims to further explore changes and possible correlation in maximum bite force (MBF), occlusal force distribution and patients' subjective perception of chewing function of endodontically treated teeth after non-surgical root canal treatment, subsequent restoration, and during long-term follow-up, along with comparing to contralateral vital teeth. Methods: Patients aged 20-60 years who underwent non-surgical root canal treatment at the Graduate Endodontic Clinic, Faculty of Dentistry, Chulalongkorn University, with the following teeth indicated for endodontic treatment. Measurements of maximum bite force (MBF) of ETT and contralateral vital teeth, relative occlusal force (ROF), and questionnaire responses, are performed at the following time points: before NS-RCT, 1 month after completion of NS-RCT (before doing restoration), 3 months after crown restoration, 1, 2 and 4 years after completion of NS-RCT. Differences in MBF and ROF over time points within subjects and differences in MBF and ROF between ETT and their contralateral vital teeth were statistically analyzed.

Conditions

Endodontically Treated Teeth

Keywords

Bite force; occlusal force distribution; Endodontically treated teeth; Chewing side preference; Endodontic restoration; Prospective study

Outcome Measures

Primary Outcomes (2)

• Maximum bite force

  Maximum bite force of the endodontically treated tooth and its contralateral tooth in each patient will be measured using the FlexiForce ELF System and FlexiForce B201 sensor.

  before NS-RCT, 1 month after completion of NS-RCT (before doing restoration), 3 months after crown restoration, 1, 2 and 4 years after completion of NS-RCT.

• Relative occlusal force

  Relative Occlusal Force are measured with the T-Scan III system. A device will be inserted into the mouth of the patients, and they are instructed to bite firmly three times at the maximum cusp intersection position.

  before NS-RCT, 1 month after completion of NS-RCT (before doing restoration), 3 months after crown restoration, 1, 2 and 4 years after completion of NS-RCT.

Secondary Outcomes (1)

• Patients' subjective perception of chewing function

  before NS-RCT, 1 month after completion of NS-RCT (before doing restoration), 3 months after crown restoration, 1, 2 and 4 years after completion of NS-RCT.

Study Arms (1)

Endodontic patient

Patients aged 20-60 years undergoing non-surgical root canal treatment and subsequent restoration at the Graduate Endodontic Clinic, Faculty of Dentistry, Chulalongkorn University, with prospective assessment of bite force and occlusal force distribution over time.

Eligibility Criteria

• Age: 20 Years - 60 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Patients who underwent non-surgical root canal treatment at the Graduate Endodontic Clinic, Faculty of Dentistry, Chulalongkorn University

You may qualify if:

• Premolars or molars diagnosed with pulp necrosis or previously initiate therapy with normal apical tissues, asymptomatic apical periodontitis, or chronic apical abscess without full coverage restoration.
• Adequate remaining tooth structure for cuspal coverage restoration.
• Presence of adjacent teeth and functional opposing natural teeth.
• No analgesics drug effect at the time of investigation or not have taken analgesics 6 hours ago.

You may not qualify if:

• Patients undergoing other dental treatments during the study period that may interfere with occlusion or bite force distribution, such as orthodontic treatment, jaw surgery, or full mouth restoration.
• Received treatments that cause weakness of the jaw and facial muscles, such as botox injections.
• History or symptoms of temporomandibular disorders (TMD)
• Periodontal disease with second- or third-degree mobility
• Teeth presenting crack lines extending into the pulp chamber floor or root canal orifices.

Sponsors & Collaborators

• Chulalongkorn University: lead

Study Sites (1)

Graduate Endodontic Clinic, Faculty of Dentistry, Chulalongkorn university

Bangkok, 10330, Thailand

Location

MeSH Terms

Conditions

Tooth, Nonvital

Condition Hierarchy (Ancestors)

Dental Pulp Diseases; Tooth Diseases; Stomatognathic Diseases

Central Study Contacts

Thanomsuk Jearanaiphaisarn

CONTACT

6622188795; thanomsuk.j@chula.ac.th

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 4 Years
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor, Department of Operative Dentistry

Study Record Dates

• First Submitted: May 31, 2026
• First Posted: June 4, 2026
• Study Start: June 8, 2026
• Primary Completion (Estimated): October 31, 2027
• Study Completion (Estimated): October 31, 2030
• Last Updated: June 4, 2026

Record last verified: 2026-05

Data Sharing

• IPD Sharing: Will not share

Locations

TH (1)