NCT07624916

Brief Summary

This study aimed to evaluate the impact of ultrasound-guided bilateral transversus abdominis plane block combined with rectus sheath block on postoperative pain and recovery after robotic colectomy under an enhanced recovery after surgery (ERAS) protocol.

Trial Health

63
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
90

participants targeted

Target at P50-P75 for phase_4

Timeline
22mo left

Started Jun 2026

Geographic Reach
1 country

1 active site

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress2%
Jun 2026Mar 2028

First Submitted

Initial submission to the registry

May 24, 2026

Completed
8 days until next milestone

Study Start

First participant enrolled

June 1, 2026

Completed
2 days until next milestone

First Posted

Study publicly available on registry

June 3, 2026

Completed
1.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 31, 2028

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 31, 2028

Last Updated

June 3, 2026

Status Verified

May 1, 2026

Enrollment Period

1.8 years

First QC Date

May 24, 2026

Last Update Submit

May 30, 2026

Conditions

Transversus Abdominis Plane BlockRobotic SurgeryColorectal CancerRectus Sheath BlockEnhanced Recovery After Surgery

Keywords

colorectal cancerrobotic colectomyenhanced recovery after surgerytransversus abdominis plane blockrectus sheath block

Outcome Measures

Primary Outcomes (3)

  • Visual Analogue Scale at Resting

    Postoperative 48 hours

  • Visual Analogue Scale at Movement

    Postoperative 48 hours

  • Postoperative Opioid Consumption

    Postoperative 48 hours

Secondary Outcomes (4)

  • Postoperative Adverse Event

    From surgery until hospital discharge

  • Time to First Ambulation

    From surgery until hospital discharge

  • Time to First Flatus

    From surgery until hospital discharge

  • Hospital Stay

    At hospital discharge

Study Arms (2)

TAP+RSB-R group

EXPERIMENTAL

TAP+RS block with ropivacaine and standard analgesic care

Drug: Ropivacaine

TAP+RSB-S group

PLACEBO COMPARATOR

TAP+RS block with saline and standard analgesic care

Drug: Saline

Interventions

RopivacaineDRUG

TAP+RS block using ropivacaine

TAP+RSB-R group
SalineDRUG

TAP+RS block with saline

TAP+RSB-S group

Eligibility Criteria

Age20 Years - 80 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patients scheduled for elective robotic colorectal cancer surgery for the first time

You may not qualify if:

  • Age \< 18 years or age \> 80 years
  • Allergic to any medication in the protocol
  • Infection over the injection site
  • Chronic pain history
  • Severe hepatic or renal insufficiency
  • Pregnancy
  • Emergency surgery
  • Refusal to join the study

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Tri-Service General Hospital

Taipei, Taiwan

Location

Related Publications (5)

  • Yang R, Wang J, Shi DW, Niu Y, Zhou XD, Liu Y, Xu GH. The Efficiency of Multipoint Rectus Sheath Block Based on Incision Location in Laparoscopic-Assisted Colorectal Surgery: A Randomized Clinical Trial. Dis Colon Rectum. 2023 Dec 1;66(12):1578-1586. doi: 10.1097/DCR.0000000000002895. Epub 2023 Jun 28.

    PMID: 37379171RESULT

  • Liu KY, Lu YJ, Lin YC, Wei PL, Kang YN. Transversus abdominis plane block for laparoscopic colorectal surgery: A meta-analysis of randomised controlled trials. Int J Surg. 2022 Aug;104:106825. doi: 10.1016/j.ijsu.2022.106825. Epub 2022 Aug 8.

    PMID: 35953018RESULT

  • Viderman D, Aubakirova M, Abdildin YG. Transversus Abdominis Plane Block in Colorectal Surgery: A Meta-Analysis. Front Med (Lausanne). 2022 Feb 23;8:802039. doi: 10.3389/fmed.2021.802039. eCollection 2021.

    PMID: 35295183RESULT

  • Liu L, Xie YH, Zhang W, Chai XQ. Effect of Transversus Abdominis Plane Block on Postoperative Pain after Colorectal Surgery: A Meta-Analysis of Randomized Controlled Trials. Med Princ Pract. 2018;27(2):158-165. doi: 10.1159/000487323. Epub 2018 Feb 1.

    PMID: 29402875RESULT

  • Hain E, Maggiori L, Prost A la Denise J, Panis Y. Transversus abdominis plane (TAP) block in laparoscopic colorectal surgery improves postoperative pain management: a meta-analysis. Colorectal Dis. 2018 Apr;20(4):279-287. doi: 10.1111/codi.14037.

    PMID: 29381824RESULT

MeSH Terms

Conditions

Colorectal Neoplasms

Interventions

RopivacaineSodium Chloride

Condition Hierarchy (Ancestors)

Intestinal NeoplasmsGastrointestinal NeoplasmsDigestive System NeoplasmsNeoplasms by SiteNeoplasmsDigestive System DiseasesGastrointestinal DiseasesColonic DiseasesIntestinal DiseasesRectal Diseases

Intervention Hierarchy (Ancestors)

AnilidesAmidesOrganic ChemicalsAniline CompoundsAminesChloridesHydrochloric AcidChlorine CompoundsInorganic ChemicalsSodium Compounds

Central Study Contacts

Wei-Cheng Tseng, MD

CONTACT

886-2-8792-3311ndmc_wechern@yahoo.com.tw

Study Design

Study Type
interventional
Phase
phase 4
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

May 24, 2026

First Posted

June 3, 2026

Study Start

June 1, 2026

Primary Completion (Estimated)

March 31, 2028

Study Completion (Estimated)

March 31, 2028

Last Updated

June 3, 2026

Record last verified: 2026-05

Data Sharing

IPD Sharing
Will not share

There is no plan to share

Locations

TW(1)