Nasal Surgery in Snoring and Obstructive Sleep Apnea

NCT07622745 | Completed

• 1 other identifier: 1225
• Study Type: interventional
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

This study aimed to evaluate the effect of isolated nasal surgery on sleep-disordered breathing, particularly apnea-hypopnea index (AHI) and snoring index (SI), Apnea index (AI) and minimal arterial oxygen saturation (MAO2) in adults with obstructive sleep apnea syndrome (OSAS) and nasal obstruction.

Conditions

Snoring; Obstructive Sleep Apnea; Nasal Surgery

Outcome Measures

Primary Outcomes (1)

• Apnea-Hypopnea Index

  The Apnea-Hypopnea Index (AHI) is a critical metric used to diagnose and rank the severity of sleep apnea. It measures the average number of times your breathing completely stops (apneas) or becomes severely shallow (hypopneas) per hour of sleep.

  3 months postoperatively

Secondary Outcomes (1)

• Snoring index

  3 months postoperatively

Study Arms (3)

Group I

EXPERIMENTAL

Patients with nasal septal deviation and hypertrophied inferior turbinate (HIT) who underwent septoplasty with partial inferior turbinectomy.

Procedure: Septoplasty with partial inferior turbinectomy

Group II

EXPERIMENTAL

Patients with chronic rhinosinusitis with nasal polyps who underwent functional endoscopic sinus surgery (FESS) with nasal polypectomy.

Procedure: Nasal polypectomy

Group III

EXPERIMENTAL

Patients with isolated hypertrophied inferior turbinate (HIT) who underwent partial inferior turbinectomy alone.

Procedure: Partial inferior turbinectomy

Interventions

Septoplasty with partial inferior turbinectomy PROCEDURE

Patients with nasal septal deviation and hypertrophied inferior turbinate (HIT) who underwent septoplasty with partial inferior turbinectomy.

Group I

Nasal polypectomy PROCEDURE

Patients with chronic rhinosinusitis with nasal polyps who underwent functional endoscopic sinus surgery (FESS) with nasal polypectomy.

Group II

Partial inferior turbinectomy PROCEDURE

Patients with isolated hypertrophied inferior turbinate (HIT) who underwent partial inferior turbinectomy alone.

Group III

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Age above 18 years.
• Both sexes.
• Patients with anatomical nasal obstruction due to septal deviation, hypertrophied inferior turbinate (HIT), or nasal polyps refractory to medical treatment.
• Presence of snoring and obstructive sleep apnea (OSA).
• Fitness for surgery.

You may not qualify if:

• Central or mixed sleep apnea.
• Previous nasal surgery.
• Unfitness for surgery.
• Pathological obesity.
• History of cardiopulmonary disease or asthma.

Sponsors & Collaborators

• Al-Azhar University: lead

Study Sites (1)

Al-Azhar University

Cairo, 11651, Egypt

Location

MeSH Terms

Conditions

Snoring; Sleep Apnea, Obstructive

Condition Hierarchy (Ancestors)

Respiratory Sounds; Signs and Symptoms, Respiratory; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Sleep Apnea Syndromes; Apnea; Respiration Disorders; Respiratory Tract Diseases; Sleep Disorders, Intrinsic; Dyssomnias; Sleep Wake Disorders; Nervous System Diseases

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Resident of Otorhinolaryngology, Faculty of Medicine, Al-Azhar University for Girls, Egypt.

Study Record Dates

• First Submitted: May 23, 2026
• First Posted: June 3, 2026
• Study Start: March 1, 2022
• Primary Completion: July 1, 2024
• Study Completion: July 1, 2024
• Last Updated: June 3, 2026

Record last verified: 2026-06

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL
• Time Frame: After the end of study for one year.
• Access Criteria: The data will be available upon a reasonable request from the corresponding author.

Locations

EG (1)