NCT07621822

Brief Summary

The goal of this clinical trial is to learn if telephone-based Acceptance and Commitment Therapy (ACT) works to help young adults with hazardous or harmful alcohol use quit drinking. It will also learn about the psychological effects of ACT on participants. The main questions it aims to answer are:

  1. 1.Does telephone-based ACT increase the number of participants who quit drinking, as confirmed by a urine test?
  2. 2.Does telephone-based ACT help participants reduce their alcohol consumption and improve their psychological flexibility?
  3. 3.Receive telephone-based ACT or social support once a week for 6 weeks Complete questionnaires about their alcohol use and psychological flexibility.
  4. 4.Keep a record of their daily alcohol consumption throughout the study using a standardised diary method.
  5. 5.Provide a urine sample at the 6-month follow-up if they report having quit drinking

Trial Health

65
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
226

participants targeted

Target at P75+ for not_applicable

Timeline
37mo left

Started Aug 2026

Typical duration for not_applicable

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

May 26, 2026

Completed
7 days until next milestone

First Posted

Study publicly available on registry

June 2, 2026

Completed
2 months until next milestone

Study Start

First participant enrolled

August 1, 2026

Expected
3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2029

Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2029

Last Updated

June 2, 2026

Status Verified

May 1, 2026

Enrollment Period

3 years

First QC Date

May 26, 2026

Last Update Submit

May 26, 2026

Conditions

Hazardous DrinkingHarmful Alcohol Use

Keywords

Acceptance and Commitment TherapyTelephone-based interventionAlcohol usePsychological flexibilityRandomized controlled trial

Outcome Measures

Primary Outcomes (1)

  • Biochemically-Validated Abstinence

    Participants who self-report quitting drinking in the past 30 days are tested for ethyl glucuronide (a by-product of alcohol metabolism) via urine strips to confirm abstinence biochemically.

    T4 (6 months after the end of the intervention)

Secondary Outcomes (3)

  • Self-Reported 30-Day Abstinence

    T0 (baseline), T1 (post-intervention), T2 (1 month after the intervention), T3 (3 months after the intervention), T4 (6 months after the intervention)

  • Reduction in Alcohol Consumption

    T1 (post-intervention), T2 (1 month after the intervention), T3 (3 months after the intervention), T4 (6 months after the intervention)

  • Psychological Flexibility Index

    T0 (baseline), T1 (post-intervention), T2 (1 month after the intervention), T3 (3 months after the intervention), T4 (6 months after the intervention)

Study Arms (2)

Telephone-Based ACT Intervention

EXPERIMENTAL

Telephone-based Acceptance and Commitment Therapy for participants

Behavioral: Telephone-Based Acceptance and Commitment Therapy (ACT)

Telephone-Based Social Support

OTHER

telephone-based social support

Behavioral: Telephone-Based Social Support

Interventions

Telephone-Based Acceptance and Commitment Therapy (ACT)BEHAVIORAL

Participants in the intervention group will receive six weekly telephone sessions of ACT (45-60 min each) from interventionist.

Telephone-Based ACT Intervention
Telephone-Based Social SupportBEHAVIORAL

Participants in the control group will receive six weekly telephone sessions of social support (45 min each) from interventionist.

Telephone-Based Social Support

Eligibility Criteria

Age18 Years - 35 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • (1) aged 18-35 years
  • (2) able to read Chinese and speak Cantonese
  • (3) have AUDIT scores ≥ 8

You may not qualify if:

  • (1) currently receiving other behavioural therapies for drinking
  • (2) has serious mental illnesses, defined as a Kessler Psychological Distress Scale score ≥ 13

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Alcohol Drinking

Condition Hierarchy (Ancestors)

Drinking BehaviorBehavior

Central Study Contacts

Ka Wai Katherine LAM, Doctor of Philosophy

CONTACT

+852 27666420kw-katherine.lam@polyu.edu.hk

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Professor

Study Record Dates

First Submitted

May 26, 2026

First Posted

June 2, 2026

Study Start (Estimated)

August 1, 2026

Primary Completion (Estimated)

August 1, 2029

Study Completion (Estimated)

August 1, 2029

Last Updated

June 2, 2026

Record last verified: 2026-05