Preoperative Fasting Duration and Gastric Residue in Pediatric Upper Gastrointestinal Endoscopy

NCT07614919 | Not Yet Recruiting

• 1 other identifier: 2024-TBEK 2026/05-10
• Study Type: observational
• Target: 110
• Locations: 1 country
• Sites: 1

Brief Summary

This retrospective observational study aims to evaluate the relationship between preoperative fasting duration and gastric residue in pediatric patients undergoing upper gastrointestinal endoscopy for gastrointestinal symptoms or pathology. The study will assess the associations between gastric residue, gastrointestinal symptoms, underlying gastrointestinal diseases, and endoscopic findings. Data will be retrospectively collected from hospital records, anesthesia records, and endoscopy reports to investigate whether prolonged fasting duration reliably predicts an empty stomach in pediatric gastrointestinal patients.

Conditions

Gastric Residue; Preoperative Fasting; Upper Gastrointestinal Endoscopy

Keywords

Fasting; Endoscopy, Gastrointestinal; Gastric Emptying; Pediatrics; Anesthesia

Outcome Measures

Primary Outcomes (1)

• Gastric Residue Severity

  Severity of endoscopically observed gastric residue during upper gastrointestinal endoscopy, categorized as none, mild, moderate, or severe according to endoscopic findings documented in medical records and endoscopy reports.

  At the time of upper gastrointestinal endoscopy

Secondary Outcomes (1)

• Clinically Relevant Gastric Residue

  At the time of upper gastrointestinal endoscopy

Study Arms (1)

Pediatric Upper Gastrointestinal Endoscopy Cohort

Pediatric patients undergoing upper gastrointestinal endoscopy for gastrointestinal symptoms or pathology will be included in this retrospective observational cohort. Data regarding demographic characteristics, gastrointestinal symptoms, preoperative fasting duration, endoscopic findings, underlying gastrointestinal diseases, medication use, and endoscopically observed gastric residue will be retrospectively evaluated using hospital records, anesthesia records, and endoscopy reports. Gastric residue severity will be categorized as none, mild, moderate, or severe.

Procedure: Upper Gastrointestinal Endoscopy

Interventions

Upper Gastrointestinal Endoscopy PROCEDURE

Upper gastrointestinal endoscopy performed for evaluation of gastrointestinal symptoms or pathology in pediatric patients. The procedure was conducted under sedation or anesthesia according to institutional clinical practice. Endoscopic findings and endoscopically observed gastric residue were retrospectively evaluated from medical records and endoscopy reports.

Pediatric Upper Gastrointestinal Endoscopy Cohort

Eligibility Criteria

• Age: 0 Years - 17 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17)
• Sampling Method: Non-Probability Sample

Study Population

Pediatric patients undergoing upper gastrointestinal endoscopy for evaluation of gastrointestinal symptoms or suspected gastrointestinal pathology at a single tertiary care center will be included in this retrospective observational study. The study population will consist of patients evaluated between January 2025 and April 2026. Data will be retrospectively obtained from hospital information systems, anesthesia records, electronic medical records, and endoscopy reports. The study will evaluate demographic characteristics, gastrointestinal symptoms, preoperative fasting duration, endoscopic findings, underlying gastrointestinal diseases, medication use, and endoscopically observed gastric residue.

You may qualify if:

• Pediatric patients aged under 18 years
• Patients who underwent upper gastrointestinal endoscopy for gastrointestinal symptoms or pathology
• Patients with available hospital records, anesthesia records, and endoscopy reports
• Patients with documented preoperative fasting duration
• Patients with documented endoscopic assessment of gastric residue

You may not qualify if:

• Patients aged 18 years or older
• Patients with missing or incomplete data for key study variables
• Patients without documented preoperative fasting duration
• Patients without documented gastric residue assessment during endoscopy
• Duplicate endoscopy records from the same patient, if only the first eligible procedure is included

Sponsors & Collaborators

• Bursa Sevket Yilmaz Training and Research Hospital: lead

Study Sites (1)

University of Health Sciences, Bursa Yuksek Ihtisas Training and Research Hospital

Yıldırım, Bursa, 16310, Turkey (Türkiye)

Location

Related Publications (3)

• Shava U, Srivastava A, Mathias A, Kumar N, Yachha SK, Gambhir S, Poddar U. Functional dyspepsia in children: A study of pathophysiological factors. J Gastroenterol Hepatol. 2021 Mar;36(3):680-686. doi: 10.1111/jgh.15193. Epub 2020 Aug 5.

  PMID: 32710649 BACKGROUND

• Santucci NR, Corsiglia J, El-Chammas K, Shumeiko O, Liu C, Kaul A. Liquid and solid gastric emptying and correlation with clinical characteristics in pediatric patients with dyspepsia. Neurogastroenterol Motil. 2024 Jan;36(1):e14701. doi: 10.1111/nmo.14701. Epub 2023 Nov 5.

  PMID: 37926966 BACKGROUND

• Frykholm P, Hansen TG, Engelhardt T. Preoperative fasting in children. The evolution of recommendations and guidelines, and the underlying evidence. Best Pract Res Clin Anaesthesiol. 2024 Jun;38(2):103-110. doi: 10.1016/j.bpa.2024.03.003. Epub 2024 Mar 16.

  PMID: 39445555 BACKGROUND

MeSH Terms

Conditions

Fasting

Interventions

Endoscopy, Digestive System

Condition Hierarchy (Ancestors)

Feeding Behavior; Behavior

Intervention Hierarchy (Ancestors)

Diagnostic Techniques, Digestive System; Diagnostic Techniques and Procedures; Diagnosis; Endoscopy; Diagnostic Techniques, Surgical; Digestive System Surgical Procedures; Surgical Procedures, Operative; Minimally Invasive Surgical Procedures

Central Study Contacts

Gürcan Güler

CONTACT

+90 541 975 0407; gurcanguler.45@gmail.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER GOV
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Medical Doctor

Study Record Dates

• First Submitted: May 22, 2026
• First Posted: May 29, 2026
• Study Start: June 1, 2026
• Primary Completion: July 1, 2026
• Study Completion: July 1, 2026
• Last Updated: May 29, 2026

Record last verified: 2026-05

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)