Home and Clinic Rehabilitation in Subacute Stroke

NCT07613554 | Not Yet Recruiting

• 1 other identifier: UOL/IREB/25/12/0044
• Study Type: interventional
• Target: 72
• Locations: 0 countries
• Sites: N/A

Brief Summary

The goal of this clinical trial is to learn if adding scheduled home-based rehabilitation to clinic-based rehabilitation improves walking ability and daily activities in people aged 40 to 50 with sub-acute stroke. The main questions it aims to answer are:

• Does adding home exercises improve walking ability in people with sub-acute stroke?
• Does adding home exercises improve the ability to do daily activities in people with sub-acute stroke? Researchers will compare clinic-based rehabilitation plus home-based rehabilitation to clinic-based rehabilitation alone to see if adding home exercises leads to better recovery after stroke. Participants will:
• Attend physical therapy at the hospital 3 days per week for 12 weeks
• Do walking practice, balance training, and leg exercises at the clinic
• Do home exercises including marching, step-ups, sit-to-stand, and balance exercises on non-clinic days (home exercise group only)
• Track home exercises using a weekly logbook
• Be tested at the start and after 12 weeks

Conditions

Sub-acute Stroke

Keywords

stroke rehabilitation; sub-acute stroke; home-based rehabilitation; clinical-based rehabilitation; functional capacity; balance; gait training; timed up and go test; Hemiplegia; Activities of daily living

Outcome Measures

Primary Outcomes (2)

• Timed Up and Go Test (TUG)

  Assesses functional mobility, balance, and gait performance. The patient stands up from a chair, walks 3 meters, turns, walks back and sits down. Time is recorded in seconds. Higher time indicates poorer mobility.

  Baseline and 12 weeks

• Lawton-Brody Instrumental Activities of Daily Living Scale (IADL)

  Assesses functional performance in daily living activities including telephone use, shopping, food preparation, housekeeping, laundry, transportation, medication management, and financial management. Scores range from 0 (fully dependent) to 8 (fully independent) for women and 0 to 5 for men."

  Baseline and 12 weeks

Study Arms (2)

Group A: Clinic-based Rehabilitation

ACTIVE COMPARATOR

Patients will receive clinic-based physiotherapy sessions three days per week, 60 minutes per session, over 12 weeks. Treatment includes gait training, lower limb coordination exercises, and balance and mobility tasks.

Behavioral: Physical Therapy Rehabilitation Program

Group B: Clinic-based plus Home-based Rehabilitation

EXPERIMENTAL

Patients will receive the same clinic-based physiotherapy program as Group A plus a structured scheduled home exercise program performed on remaining days, tracked via a weekly logbook over 12 weeks.

Behavioral: Physical Therapy Rehabilitation Program

Interventions

Physical Therapy Rehabilitation Program BEHAVIORAL

A structured physical therapy program including gait training, lower limb coordination, balance and mobility tasks for clinic sessions, and home exercises including supported marching, step-ups, sit-to-stand, partial squats, and balance exercises.

Also known as: Home-based Rehabilitation Program

Group A: Clinic-based Rehabilitation; Group B: Clinic-based plus Home-based Rehabilitation

Eligibility Criteria

• Age: 40 Years - 50 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Age 40-50 years old Male and female Patients having stroke 3 months to 6 months prior to enrollment Able to comprehend and adhere to instructions Grade 1+ spasticity on Modified Ashworth Scale Modified Rankin Scale score of 3-4 with ability to maintain sitting balance for at least 1 hour

You may not qualify if:

• Myocardial infarction Other neurological deficits leading to disability Contractures Severe dysphasia and cognitive impairment Need for further surgery or medical care

Sponsors & Collaborators

• University of Lahore: lead

MeSH Terms

Conditions

Hemiplegia

Condition Hierarchy (Ancestors)

Paralysis; Neurologic Manifestations; Nervous System Diseases; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Masking Details: This is a single-blinded study. Only the outcomes assessor is blinded to group allocation. Blinding of participants and care providers was not possible due to the nature of the physical therapy interventions.
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: two parallel groups: Group A receiving clinic-based rehabilitation and Group B receiving clinic-based rehabilitation plus scheduled home-based rehabilitation, over 12 weeks.

Study Record Dates

• First Submitted: May 21, 2026
• First Posted: May 29, 2026
• Study Start: June 1, 2026
• Primary Completion (Estimated): January 1, 2027
• Study Completion (Estimated): March 1, 2027
• Last Updated: May 29, 2026

Record last verified: 2026-05