Impact of Traumatic Brain Injury on Cognitive Function, Balance and Functional Independence in Children

NCT07612410 | Active Not Recruiting

• 1 other identifier: 012/005949
• Study Type: observational
• Target: 48
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of the study is to determine the impact of different levels of traumatic brain injury on cognitive function, functional independence and balance on children and relation of cognitive dysfunction, balance disturbance and functional independence

Conditions

Traumatic Brain Injury

Keywords

BALANCE; CHILDREN; COGNITIVE FUNCTION; FUNCTIONAL INDEPENDENCE; TRAUMATIC BRAIN INJURY

Outcome Measures

Primary Outcomes (2)

• COGNITIVE FUNCTION

  The Wechsler Intelligence Scale for Children- Fourth Edition (WISC-IV) assessment containing fifteen subtests

  60:120 minutes

• balance

  Bruininks-Oseretsky Test of Motor Proficiency is a commonly diagnostic instrument in the evaluation of the development of psychometrics . It is categorized into four composite motor domains each one containing two motor subtests

  15:25 minute

Study Arms (2)

Group A. 24 children with traumatic brain injury from both sexes will participate in this s

traumatic brain injury

24 normal volunteer children for age matching group. They will be selected from Zagazig universit

normal volunteer children for age matching group

Eligibility Criteria

• Age: 8 Years - 12 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17)
• Sampling Method: Probability Sample

Study Population

24 children with traumatic brain injury from both sexes will participate in this study and 24 normal volunteer children for age matching group.

You may qualify if:

• Children diagnosed with mild to moderate traumatic brain injury.
• Their chronological age will be ranged from 8 years to 12 years.
• All subjects medically controlled immediately after discharge.

You may not qualify if:

• children with other neurological impairments or epilepsy.
• Visual or hearing impairment
• Motor or behavioral disorders before trauma such as Developmental Coordination Disorder (DCD) or Attention Deficit Hyperactive Disorder (ADHD).
• Receiving medical drugs that can cause confusion or make child less alert.
• any chronic diseases as cardiac or lung disease.
• musculoskeletal contracture or disease.

Sponsors & Collaborators

• Cairo University: lead

Study Sites (1)

Cairo University

Cairo, 02, Egypt

Location

Related Publications (1)

• Andelic, N., Løvstad, M., Norup, A., Ponsford, J., & Røe, C. (2019). Editorial: Impact of Traumatic Brain Injuries on Participation in Daily Life and Work: Recent Research and Future Directions. Front Neurol, 10, 1153. https://doi.org/10.3389/fneur.2019.01153 Barman, A., Chatterjee, A., & Bhide, R. (2016). Cognitive Impairment and Rehabilitation Strategies After Traumatic Brain Injury. Indian J Psychol Med, 38(3), 172-181. https://doi.org/10.4103/0253-7176.183086 Bidzan-Bluma, I., & Lipowska, M. (2018). Physical Activity and Cognitive Functioning of Children: A Systematic Review. Int J Environ Res Public Health, 15(4). https://doi.org/10.3390/ijerph15040800 Bland, D. C., Zampieri, C., & Damiano, D. L. (2011). Effectiveness of physical therapy for improving gait and balance in individuals with traumatic brain injury: a systematic review. Brain injury, 25(7-8), 664-679. Bronstein, A. M. (2016). Multisensory integration in balance control. Handb Clin Neurol, 137, 57-66. https://doi.org/10.1016/b978-0-444-63437-5.00004-2 Bruininks, P., & Malle, B. F. (2005). Distinguishing hope from optimism and related affective states. Motivation and emotion, 29, 324-352. Capizzi, A., Woo, J., & Verduzco-Gutierrez, M. (2020). Traumatic Brain Injury: An Overview of Epidemiology, Pathophysiology, and Medical Management. Med Clin North Am, 104(2), 213-238. https://doi.org/10.1016/j.mcna.2019.11.001 Chen, M., Dutt, A. S., & Nair, R. (2022). Systematic review of reviews on Activities of Daily Living measures for children with developmental disabilities. Heliyon, 8(6), e09698. https://doi.org/10.1016/j.heliyon.2022.e09698 Dewan, M. C., Rattani, A., Gupta, S., Baticulon, R. E., Hung, Y. C., Punchak, M., Agrawal, A., Adeleye, A. O., Shrime, M. G., Rubiano, A. M., Rosenfeld, J. V., & Park, K. B. (2018). Estimating the global incidence of traumatic brain injury. J Neurosurg, 130(4), 1080-1097. https://doi.org/10.3171/2017.10.Jns17352 Eriksen, B. A., & Eriksen, C. W. (1974). Effects of

  BACKGROUND

MeSH Terms

Conditions

Brain Injuries, Traumatic

Condition Hierarchy (Ancestors)

Brain Injuries; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Craniocerebral Trauma; Trauma, Nervous System; Wounds and Injuries

Study Officials

• manal S.Eid abd elwahab, professor of physical therapy

  prof cairo university

  STUDY CHAIR

• Alaa F hassan, lecturer

  lecturer

  STUDY DIRECTOR

• mustafa A EL Zohiery, lecturer

  lecturer cairo university

  STUDY DIRECTOR

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: assistant lecturer

Study Record Dates

• First Submitted: May 18, 2026
• First Posted: May 28, 2026
• Study Start: July 14, 2025
• Primary Completion: February 22, 2026
• Study Completion: July 1, 2026
• Last Updated: May 28, 2026

Record last verified: 2026-05

Locations

EG (1)