NCT07605910

Brief Summary

Genetic basis of musculoskeletal status malocclusions

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Timeline
Completed

Started Feb 2013

Longer than P75 for all trials

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 1, 2013

Completed
3.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2016

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2016

Completed
9.5 years until next milestone

First Submitted

Initial submission to the registry

May 18, 2026

Completed
8 days until next milestone

First Posted

Study publicly available on registry

May 26, 2026

Completed
Last Updated

May 26, 2026

Status Verified

July 1, 2016

Enrollment Period

3.8 years

First QC Date

May 18, 2026

Last Update Submit

May 18, 2026

Conditions

Malocclusions

Outcome Measures

Primary Outcomes (1)

  • expression levels of genes involved in regulating the masseter phenotype

    to correlate the expression levels of genes involved in regulating the masseter phenotype and jaw growth with different groups of malocclusions

    inclusion time

Eligibility Criteria

Age13 Years - 65 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Study Population

Patients scheduled to undergo orthognathic surgery to correct their dento-maxillofacial deformity in Prof. Ferri's department and who have either Class II or Class III malocclusion.

You may qualify if:

  • Patients scheduled to undergo orthognathic surgery to correct their dento-maxillofacial deformity in Prof. Ferri's department and who have either Class II or Class III malocclusion.

You may not qualify if:

  • Pregnant or breastfeeding women

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Malocclusion

Condition Hierarchy (Ancestors)

Tooth DiseasesStomatognathic Diseases

Study Design

Study Type
observational
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 18, 2026

First Posted

May 26, 2026

Study Start

February 1, 2013

Primary Completion

December 1, 2016

Study Completion

December 1, 2016

Last Updated

May 26, 2026

Record last verified: 2016-07

Data Sharing

IPD Sharing
Will not share