NCT07605221

Brief Summary

The goal of this clinical trial is to learn if nomogram could promote treatment outcomes in astigmatism correction. The main question it aims to answer is: does the nomogram could promote treatment outcomes in astigmatism correction? If there is a comparison group: Researchers will compare non-nomogram adopted to see if the outcome acceptable. Participants will ask to complete 3-month follow-up of manifest refraction and visual acuity test.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
100

participants targeted

Target at P50-P75 for not_applicable

Timeline
20mo left

Started Feb 2025

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress44%
Feb 2025Dec 2027

Study Start

First participant enrolled

February 18, 2025

Completed
1.2 years until next milestone

First Submitted

Initial submission to the registry

May 18, 2026

Completed
4 days until next milestone

First Posted

Study publicly available on registry

May 22, 2026

Completed
7 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2026

Expected
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2027

Last Updated

May 22, 2026

Status Verified

May 1, 2026

Enrollment Period

1.9 years

First QC Date

May 18, 2026

Last Update Submit

May 18, 2026

Conditions

Astigmatism

Outcome Measures

Primary Outcomes (1)

  • residual astigmstism

    3 months

Secondary Outcomes (1)

  • visual acuity

    3 months

Study Arms (2)

nomogram group

EXPERIMENTAL

astigmatism was corrected with nomogram adjustment

Procedure: nomogram

control group

NO INTERVENTION

astigmatism was corrected without nomogram adjustment

Interventions

nomogramPROCEDURE

nomogram was added to nomogram group

nomogram group

Eligibility Criteria

Age18 Years - 45 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • age ≥18 years; preoperative sphere -0.50 D to -10.00 D; preoperative cylinder -1.50 D to -5.00 D; stable refraction (±0.50 D) for 1 year; normal corneal topography; central corneal thickness \>500 μm or predicted residual stromal bed \>280 μm; intraocular pressure \<21 mmHg

You may not qualify if:

  • ocular or systematic disease

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Tianjin Eye Hospital

Tianjin, Tianjin Municipality, 300000, China

RECRUITING

MeSH Terms

Conditions

Astigmatism

Interventions

Nomograms

Condition Hierarchy (Ancestors)

Refractive ErrorsEye Diseases

Intervention Hierarchy (Ancestors)

PrognosisDiagnosisModels, StatisticalStatistics as TopicEpidemiologic MethodsInvestigative TechniquesModels, TheoreticalMathematical ConceptsHealth Care Evaluation MechanismsQuality of Health CareHealth Care Quality, Access, and EvaluationPublic HealthEnvironment and Public Health

Central Study Contacts

Jiamei Zhang

CONTACT

022-27305083jiamei3536@163.com

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 18, 2026

First Posted

May 22, 2026

Study Start

February 18, 2025

Primary Completion (Estimated)

December 31, 2026

Study Completion (Estimated)

December 31, 2027

Last Updated

May 22, 2026

Record last verified: 2026-05

Locations

CN(1)