Epicardial Fat Tissue and Cardiometabolic Risk in Russian and Asian Populations
EPIGRAPH
Epicardial Fat Tissue Assessed by Echocardiography in Russian and Asian Populations: Association With Chronic Non-Communicable Diseases and Risk Factors
1 other identifier
observational
500
1 country
1
Brief Summary
Visceral obesity is a well-established risk factor for the development of chronic non-communicable diseases (NCDs). Epicardial fat tissue (EFT) is located on the surface of the myocardium and may directly affect cardiac function and contribute to structural and functional remodeling. According to the literature, increased EFT thickness is associated with a wide range of NCDs, disease severity, and prognosis. The aim of this study is to investigate the associations between EFT thickness and clinical and anamnestic parameters, as well as to evaluate the prognostic value of this parameter in patients aged 50-70 years from the Russian Federation, Kazakhstan, Uzbekistan, and Kyrgyzstan.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started May 2026
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
May 4, 2026
CompletedFirst Submitted
Initial submission to the registry
May 18, 2026
CompletedFirst Posted
Study publicly available on registry
May 22, 2026
CompletedPrimary Completion
Last participant's last visit for primary outcome
March 1, 2027
ExpectedStudy Completion
Last participant's last visit for all outcomes
March 1, 2028
May 22, 2026
May 1, 2026
10 months
May 18, 2026
May 18, 2026
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Composite endpoint - all-cause mortality - hospitalizations - major adverse cardiovascular events (MACE)
12 months
Study Arms (1)
Observational cohort
Patients aged 50-70 years undergoing transthoracic echocardiography (TTE) in inpatient or outpatient
Eligibility Criteria
Patients from the Russian Federation, Kazakhstan, Uzbekistan, and Kyrgyzstan
You may qualify if:
- Patients aged 50-70 years undergoing transthoracic echocardiography in inpatient or outpatient settings;
- Ability and willingness to provide informed consent.
You may not qualify if:
- Refusal to sign informed consent;
- Inability to perform transthoracic echocardiography or poor image quality;
- Severe psychiatric disorders.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
National Medical Research Center for Therapy and Preventive Medicine
Moscow, Russia
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- CROSS SECTIONAL
- Sponsor Type
- OTHER GOV
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
May 18, 2026
First Posted
May 22, 2026
Study Start
May 4, 2026
Primary Completion (Estimated)
March 1, 2027
Study Completion (Estimated)
March 1, 2028
Last Updated
May 22, 2026
Record last verified: 2026-05