NCT07604155

Brief Summary

28 patients will be included in this study with atrophic posterior maxillary ridge due to sinus pneumatization who will randomly assigned to two groups

  • Group I: sinus lifting using CAD/CAM allogenic block through lateral window technique
  • Group II: sinus lifting using particulate allogenic graftthrough lateral window technique

Trial Health

75
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
28

participants targeted

Target at below P25 for not_applicable

Timeline
10mo left

Started Sep 2025

Geographic Reach
1 country

1 active site

Status
enrolling by invitation

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress47%
Sep 2025Mar 2027

Study Start

First participant enrolled

September 3, 2025

Completed
9 months until next milestone

First Submitted

Initial submission to the registry

May 17, 2026

Completed
5 days until next milestone

First Posted

Study publicly available on registry

May 22, 2026

Completed
7 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 10, 2026

Expected
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

March 19, 2027

Last Updated

May 22, 2026

Status Verified

May 1, 2026

Enrollment Period

1.3 years

First QC Date

May 17, 2026

Last Update Submit

May 17, 2026

Conditions

Keywords

CAD-CAM allogenic blockparticulate allograftsinus lifting

Outcome Measures

Primary Outcomes (2)

  • bone height gain

    using CBCT

    6 months

  • marginal bone resorption around implants

    CBCT

    6 months

Study Arms (2)

CAD/CAM allogenic block

EXPERIMENTAL

sinus lifting using CAD/CAM allogenic block through lateral window technique

Procedure: sinus lifting using CAD/CAM allogenic block

particulate allogenic graft

EXPERIMENTAL

sinus lifting using particulate allogenic graft through lateral window technique

Procedure: sinus lifting using particulate allogenic graft

Interventions

A full-thickness, wide mucoperiosteal flap was elevated buccally. A lateral bony window of the maxillary sinus will be made, then the sinus lining will be carefully elevated. The CAD/CAM allogenic block will be inserted and fixed in its position via a titanium screw to the crest of maxillary ridge (group I). • The lateral window will be covered with collagen membrane, the flap will be repositioned in its place and sutured.

CAD/CAM allogenic block

In group II the particulate bone will packed at the site of augmentation

particulate allogenic graft

Eligibility Criteria

Age20 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • above 20 years
  • ridge height less than or equal to 5 mm
  • healthy clear sinus

You may not qualify if:

  • systemic disease affect bone healing
  • heavy smokers
  • disease or pathology within the sinus

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Faculty of Dentistry, Tanta University

Tanta, 3111, Egypt

Location

Study Officials

  • mohamed h helal, lecturer

    Tanta University

    PRINCIPAL INVESTIGATOR
  • rehab ghouraba, professor

    Tanta University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
TRIPLE
Who Masked
PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
Masking Details
Outcome assessor other than operators groups were blinded to investigator and patients
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
lecturer of oral and maxillofacial surgery

Study Record Dates

First Submitted

May 17, 2026

First Posted

May 22, 2026

Study Start

September 3, 2025

Primary Completion (Estimated)

December 10, 2026

Study Completion (Estimated)

March 19, 2027

Last Updated

May 22, 2026

Record last verified: 2026-05

Locations