NCT07603206

Brief Summary

The goals of this study are to determine if replacing gas stoves with portable electric hot plates and electric toaster ovens will improve indoor air quality and asthma control. Researchers will enroll participants with poorly controlled asthma and provide them with hot plates and toaster ovens to use instead of gas stoves. Researchers will measure indoor air quality about 1-2 weeks before and about 2-3 months after providing portable appliances. Participants will answer questions about their asthma symptoms and take lung function tests about 1-2 weeks before and about 2-3 months after using portable appliances.

Trial Health

65
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
20

participants targeted

Target at below P25 for not_applicable

Timeline
36mo left

Started Jun 2026

Typical duration for not_applicable

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress1%
Jun 2026May 2029

First Submitted

Initial submission to the registry

April 28, 2026

Completed
24 days until next milestone

First Posted

Study publicly available on registry

May 22, 2026

Completed
10 days until next milestone

Study Start

First participant enrolled

June 1, 2026

Completed
2.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2029

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2029

Last Updated

May 22, 2026

Status Verified

May 1, 2026

Enrollment Period

2.9 years

First QC Date

April 28, 2026

Last Update Submit

May 19, 2026

Conditions

Asthma Control

Keywords

asthmaindoor air quality

Outcome Measures

Primary Outcomes (2)

  • Change in asthma control

    Change in Asthma Control Questionnaire score from baseline to final assessment. Asthma Control Questionnaire scores can range from 0 to 6 with higher scores indicating poor asthma control.

    Baseline assessment 1-2 weeks before portable appliances given to participant. Final assessment 2-3 months after portable appliances given to participant.

  • Change in indoor nitrogen dioxide levels

    Change in nitrogen dioxide level from baseline to final assessment

    Baseline assessment 1-2 weeks before portable appliances given to participant. Final assessment 2-3 months after portable appliances given to participant.

Secondary Outcomes (1)

  • Change in forced expiratory volume in 1 second (FEV1)

    Baseline assessment 1-2 weeks before portable appliances given to participant. Final assessment 2-3 months after portable appliances given to participant.

Study Arms (2)

Immediate Intervention

EXPERIMENTAL

Participants will receive electric hotplate and electric toaster oven immediately after enrollment.

Other: Portable cooking appliances

Delayed Intervention

EXPERIMENTAL

Participants will receive electric hotplate and electric toaster oven six months after enrollment.

Other: Portable cooking appliances

Interventions

Portable cooking appliancesOTHER

The investigators will leave gas stoves in place but will instruct participants to preferentially use two relatively inexpensive portable electric appliances that the investigators will provide. Cooking will be done with an electric induction hot plate and baking with an electric toaster oven.

Delayed InterventionImmediate Intervention

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Currently use gas stove for cooking or baking at least three times a week
  • Poorly controlled asthma as defined by an Asthma Control Questionnaire score of 1.5 or larger

You may not qualify if:

  • Impaired decision making capacity
  • Pregnancy

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (3)

  • Bime C, Nguyen J, Wise RA. Measures of asthma control. Curr Opin Pulm Med. 2012 Jan;18(1):48-56. doi: 10.1097/MCP.0b013e32834db0f2.

    PMID: 22081089BACKGROUND

  • Audignon-Durand S, Ramalho O, Mandin C, Roudil A, Le Bihan O, Delva F, Lacourt A. Indoor exposure to ultrafine particles related to domestic activities: A systematic review and meta-analysis. Sci Total Environ. 2023 Dec 15;904:166947. doi: 10.1016/j.scitotenv.2023.166947. Epub 2023 Sep 9.

    PMID: 37690752BACKGROUND

  • Lebel ED, Finnegan CJ, Ouyang Z, Jackson RB. Methane and NOx Emissions from Natural Gas Stoves, Cooktops, and Ovens in Residential Homes. Environ Sci Technol. 2022 Feb 15;56(4):2529-2539. doi: 10.1021/acs.est.1c04707. Epub 2022 Jan 27.

    PMID: 35081712BACKGROUND

MeSH Terms

Conditions

Asthma

Condition Hierarchy (Ancestors)

Bronchial DiseasesRespiratory Tract DiseasesLung Diseases, ObstructiveLung DiseasesRespiratory HypersensitivityHypersensitivity, ImmediateHypersensitivityImmune System Diseases

Central Study Contacts

Ash Sehgal, MD

CONTACT

216-778-7728axs81@cwru.edu

Ther Aung, PhD

CONTACT

216-778-4061taung@metrohealth.org

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
CROSSOVER
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

April 28, 2026

First Posted

May 22, 2026

Study Start

June 1, 2026

Primary Completion (Estimated)

May 1, 2029

Study Completion (Estimated)

May 1, 2029

Last Updated

May 22, 2026

Record last verified: 2026-05

Data Sharing

IPD Sharing
Will not share