External Oblique Intercostal Fascial Plane Block Versus Rectus Sheath Block for Postoperative Analgesia

NCT07601945 | Completed Phase 3

• 1 other identifier: EOIPB
• Study Type: interventional
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

This study aimed to compare the analgesic efficacy of the external oblique intercostal fascial plane block (EOIPB) versus the rectus sheath block (RSB) for managing postoperative pain following paraumbilical hernioplasty.

Conditions

External Oblique Intercostal Fascial Plane Block; Rectus Sheath Block; Pain

Keywords

External Oblique Intercostal Fascial Plane Block; Rectus Sheath Block; Pain

Outcome Measures

Primary Outcomes (2)

• Total postoperative morphine consumption in milligrams during the first 24 hours after surgery

  Total cumulative morphine requirement administered for postoperative analgesia during the first 24 hours following paraumbilical hernia repair surgery, measured in milligrams (mg).

  First 24 hours postoperatively

• Number of participants experiencing block-related or postoperative complications within 3 months after surgery

  Assessment of postoperative and block-related complications including local anesthetic toxicity, hematoma, infection, nausea/vomiting, respiratory depression, and other adverse events recorded during the follow-up period.

  3 months after surgery

Study Arms (2)

external oblique intercostal fascial plane block

EXPERIMENTAL

external oblique intercostal fascial plane block

Procedure: External Oblique Intercostal Fascial Plane Block for Postoperative Analgesia

rectus sheath block

ACTIVE COMPARATOR

rectus sheath block

Procedure: External Oblique Intercostal Fascial Plane Block for Postoperative Analgesia

Interventions

External Oblique Intercostal Fascial Plane Block for Postoperative Analgesia PROCEDURE

After the induction of general anesthesia and approximately 15 minutes before the surgical incision, patients were randomly assigned to receive either the EOIPB (Group A) or the RSB (Group B).

external oblique intercostal fascial plane block; rectus sheath block

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Patients aged 18-65 years, classified as American Society of Anesthesiologists (ASA) physical status I or II \[16\], and scheduled for elective paraumbilical hernioplasty.

You may not qualify if:

• Patients with a history of prolonged opioid medication, allergy to local anesthetics, pregnancy, infection at the injection site, and/or coagulopathy.

Sponsors & Collaborators

• Helwan University: lead

Study Sites (1)

Helwan university

Giza, Giza Governorate, 3030, Egypt

Location

MeSH Terms

Conditions

Pain

Condition Hierarchy (Ancestors)

Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: interventional
• Phase: phase 3
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Prof

Model Details: This prospective, randomized, single-blinded study enrolled 60 patients, divided into two groups (EOIPB and RSB), each comprising 30 participants

Study Record Dates

• First Submitted: April 26, 2026
• First Posted: May 22, 2026
• Study Start: May 1, 2023
• Primary Completion: April 30, 2025
• Study Completion: June 30, 2025
• Last Updated: May 22, 2026

Record last verified: 2026-04

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL

Locations

EG (1)