Comparison of Interrupted Suturing Versus Continuous Suturing in Laparotomy Wound Closed.

NCT07601919 | Completed

• 1 other identifier: Dr-Farhan-Rawalpindi
• Study Type: interventional
• Target: 184
• Locations: 1 country
• Sites: 1

Brief Summary

Emergency laparotomy is associated with high morbidity, particularly due to wound dehiscence and infection. Choosing an optimal suturing technique can significantly impact patient outcomes, but data on the comparison of interrupted suturing with continuous suturing in emergency settings is limited. Therefore, the current study was planned, aiming to compare the outcome of emergency laparotomy wounds closed by interrupted suturing versus continuous suturing.

Conditions

Surgical Wound

Outcome Measures

Primary Outcomes (2)

• Wound dehiscence

  The frequency of patients who experienced spontaneous opening of the midline laparotomy sutures within 10 days of surgery was noted.

  10 days

• Wound infection

  The frequency of patients who showed the presence of pus or any discharge at the surgical wound site, which was accompanied by pain, fever, raised white blood cell count (\> 11000), swelling, and erythema, was noted.

  10 days

Study Arms (2)

Group-A

EXPERIMENTAL

Patients went through interrupted closure with Smead Jones technique using prolene 1.

Procedure: Interrupted Closure

Group-B

EXPERIMENTAL

Patients went through continuous closure with prolene 1.

Procedure: Continuous Closure

Interventions

Interrupted Closure PROCEDURE

Patients went through interrupted closure with Smead Jones technique using prolene 1.

Group-A

Continuous Closure PROCEDURE

Patients went through continuous closure with prolene 1.

Group-B

Eligibility Criteria

• Age: 18 Years - 60 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Patients of either gender
• Aged 18-60 years
• Undergoing emergency laparotomy

You may not qualify if:

• Unfit for surgery
• History of diabetes
• Immuno-compromised
• Pregnant/lactating mothers
• Malignancy
• Very low or very high body mass index (\< 15kg/m2 or \> 30kg/m2)

Sponsors & Collaborators

• Muhammad Aamir Latif: lead

Study Sites (1)

Benazir Bhutto Hospital/Rawalpindi Medical University and Allied Hospitals

Rawalpindi, Punjab Province, 46000, Pakistan

Location

MeSH Terms

Conditions

Surgical Wound

Condition Hierarchy (Ancestors)

Wounds and Injuries

Study Officials

• Farhan Ahmed

  Benazir Bhutto Hospital/Rawalpindi Medical University and Allied Hospitals, Rawalpindi

  PRINCIPAL INVESTIGATOR

• Usman Qureshi, FCPS

  Holy Family Hospital/Rawalpindi Medical University and Allied Hospitals, Rawalpindi

  STUDY DIRECTOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Research Consultant

Study Record Dates

• First Submitted: May 15, 2026
• First Posted: May 22, 2026
• Study Start: August 15, 2025
• Primary Completion: February 14, 2026
• Study Completion: February 14, 2026
• Last Updated: May 22, 2026

Record last verified: 2026-05

Data Sharing

• IPD Sharing: Will not share

Locations

PA (1)