Establish Whether Hyperangulated Videolaryngoscopy (HAVL) Can be Used to Facilitate Tracheal Intubation Effectively and Safely in Unselected Adult Patients; Describe the Population in Whom HAVL Fails to Facilitate Tracheal Intubation Successfully, Identifying Any Contributory Characteristics.

NCT07600502 | Not Yet Recruiting

• 1 other identifier: 350850
• Study Type: interventional
• Target: 500
• Locations: 1 country
• Sites: 1

Brief Summary

When patients have a general anaesthetic (go to sleep for surgery), the anaesthetist often places a small tube into their windpipe (intubation) to help them breathe. To see exactly where to put the tube, the anaesthetist uses a device called a laryngoscope. A commonly used laryngoscope is the McGrath videolaryngoscope. It has a small camera and screen to help guide safe placement of the tube. It comes in two different shapes - one shaped in the same way laryngoscopes have been shaped for the last 80 years, and another newer design (McGrath X-blade) that matches the curve of patients' tongues better. All different classes of videolaryngoscope have been shown to have benefits to patients; however, the best videolaryngoscope shape has yet to be determined. The McGrath X-blade is currently recommended in patients in whom the anaesthetist thinks it might be slightly more difficult to place the tube, but some anaesthetists already prefer to use it in all their patients. This is not a new device or a new technique. In this study, the investigators wish to explore if there is any special benefit of using it in all patients, by collecting some information when the device is used.

Conditions

Intubation Skill; Intubation Complications; Intubation With Uncuffed Endotracheal Tube

Keywords

videolaryngoscopy; hyperangulated blade; first-pass success; airway management

Outcome Measures

Primary Outcomes (1)

• First-pass success

  Incidence of successful tracheal intubation at the first attempt (without complications) using the McGrath-X blade

  5 minutes

Secondary Outcomes (2)

• Overall incidence of tracheal intubation success

  5 minutes

• Incidence of complications

  5 minutes

Study Arms (1)

Use of McGrath X-blade to facilitate tracheal intubation

EXPERIMENTAL

Unselected adult patients who have been assessed as requiring tracheal intubation for their surgical intervention/ongoing care, will undergo their intubation procedure facilitated by McGrath X-blade

Device: Hyperangulated videolaryngoscopy

Interventions

Hyperangulated videolaryngoscopy DEVICE

Hyperangulated videolaryngoscopy using McGrath X-blade

Use of McGrath X-blade to facilitate tracheal intubation

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Adult patients undergoing surgical procedures requiring tracheal intubation as part of their routine anaesthetic care
• Patients undergoing either naso- or oro-tracheal intubation
• Patients undergoing tracheal intubation with or without administration of neuromuscular blocking agents (e.g. those undergoing surgery where facial nerve or recurrent laryngeal nerve monitoring will be utilised)

You may not qualify if:

• Patients \<18 years of age
• Patients in whom tracheal intubation is not required as part of their routine anaesthetic care

Sponsors & Collaborators

• NHS Lothian: lead
• Medtronic: collaborator

Study Sites (1)

St John's Hospital

Livingston, United Kingdom

Location

Related Publications (2)

• Saul SA, Ward PA, McNarry AF. Airway Management: The Current Role of Videolaryngoscopy. J Pers Med. 2023 Aug 29;13(9):1327. doi: 10.3390/jpm13091327.

  PMID: 37763095 BACKGROUND

• Hansel J, Rogers AM, Lewis SR, Cook TM, Smith AF. Videolaryngoscopy versus direct laryngoscopy for adults undergoing tracheal intubation: a Cochrane systematic review and meta-analysis update. Br J Anaesth. 2022 Oct;129(4):612-623. doi: 10.1016/j.bja.2022.05.027. Epub 2022 Jul 9.

  PMID: 35820934 BACKGROUND

Study Officials

• Patrick A Ward

  NHS Lothian

  STUDY DIRECTOR

Central Study Contacts

Patrick A Ward

CONTACT

+44(0)1506523064; patrick.ward@nhs.scot

Pamela Milligan

CONTACT

+44(0)1506523064; pamela.milligan@nhs.scot

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: OTHER
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER GOV
• Responsible Party: SPONSOR

Model Details: Define the patient population in whom an approved well-established medical device can be used optimally

Study Record Dates

• First Submitted: April 30, 2026
• First Posted: May 20, 2026
• Study Start (Estimated): June 1, 2026
• Primary Completion (Estimated): June 1, 2027
• Study Completion (Estimated): September 1, 2027
• Last Updated: May 20, 2026

Record last verified: 2026-05

Data Sharing

• IPD Sharing: Will not share

Locations

GB (1)