Endoscopic Versus Conventional Parotidectomy for Benign Parotid Tumors

NCT07600112 | Active Not Recruiting

• 1 other identifier: endo-parotidectomy
• Study Type: interventional
• Target: 46
• Locations: 1 country
• Sites: 1

Brief Summary

To compare endoscopic and conventional parotidectomy in the management of benign parotid tumors regarding surgical outcomes, facial nerve preservation, operative time, postoperative complications, and cosmetic results, in order to evaluate the safety, feasibility, and potential advantages of the endoscopic minimally invasive technique.

Conditions

Parotidectomy

Keywords

parotidectomy

Outcome Measures

Primary Outcomes (2)

• Surgical safety and feasibility

  Assessment of intraoperative and postoperative complications and conversion rate to open surgery.

  During surgery and up to 3 months postoperatively.

• Facial nerve function

  Assessment using House-Brackmann grading system.

  24 hours, 1 week, 1 month, and 3 months postoperatively.

Secondary Outcomes (1)

• Intraoperative blood loss

  Intraoperative

Study Arms (2)

Endoscopic Parotidectomy Group

EXPERIMENTAL

Experimental Arm Endoscopic Parotidectomy

Procedure: Endoscopic Parotidectomy Group

Conventional Open Parotidectomy Group

ACTIVE COMPARATOR

Conventional Parotidectomy

Procedure: Active Comparator Intervention Conventional Parotidectomy

Interventions

Endoscopic Parotidectomy Group PROCEDURE

Minimally invasive endoscopic-assisted parotidectomy performed through anterior chest wall approach for benign parotid tumors.

Endoscopic Parotidectomy Group

Active Comparator Intervention Conventional Parotidectomy PROCEDURE

Conventional open parotidectomy performed through modified Blair incision for management of benign parotid tumors.

Conventional Open Parotidectomy Group

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Adults aged 18 years or older
• Patients with benign parotid tumors involving the superficial lobe of the parotid gland
• Tumors located in the inferior pole with or without limited deep lobe extension
• Tumor size suitable for minimally invasive approach ≤4 cm
• Patients fit for surgery under general anesthesia
• Patients willing to provide informed consent and comply with follow-up

You may not qualify if:

• Recurrent parotid tumors
• Previous parotid surgery on the affected side
• Pre-existing facial nerve dysfunction
• Previous neck surgery or extensive cervical/anterior chest wall scarring
• Significant comorbidities contraindicating surgery or general anesthesia
• Suspected or confirmed malignant parotid tumors

Sponsors & Collaborators

• Assiut University: lead

Study Sites (1)

Department of General Surgery, Maxillofacial and Head and Neck Unit

Asyut, 2063045, Egypt

Location

Related Publications (1)

• O'Brien CJ. Current management of benign parotid tumors--the role of limited superficial parotidectomy. Head Neck. 2003 Nov;25(11):946-52. doi: 10.1002/hed.10312.

  PMID: 14603455 BACKGROUND

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Model Details: prospective randomized controlled parallel assignment

Study Record Dates

• First Submitted: May 15, 2026
• First Posted: May 20, 2026
• Study Start: May 1, 2026
• Primary Completion (Estimated): December 29, 2026
• Study Completion (Estimated): June 1, 2028
• Last Updated: May 20, 2026

Record last verified: 2026-05

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)