LONG PULSED ND:YAG LASER (1064 NM) VERSUS INTENSE PULSED LIGHT IN TREATMENT OF TRAUMATIC AND POST-SURGICAL ERYTHEMATOUS SCARS

NCT07599709 | Completed FDA Device

• 1 other identifier: 0107942
• Study Type: interventional
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this clinical trial is to compare the efficacy and safety of long-pulsed ND:YAG laser and intense pulsed light in the treatment of traumatic and post-surgical erythematous scars. Forty patients presenting with traumatic and post-surgical erythematous scars on the head and neck, of six months' duration or less, were randomly divided into two equal groups. Group A patients received long-pulsed ND:YAG laser sessions, while Group B patients received intense pulsed light sessions. Four sessions were given at four-week intervals.

Conditions

Scars

Keywords

erythematous scars; traumatic scars; post-surgical scars

Outcome Measures

Primary Outcomes (1)

• Compare the efficacy and safety of long-pulsed Nd-YAG laser and intense pulsed light in the treatment of traumatic and post-surgical erythematous scars.

  The efficacy were assessed using the Patient and Observer scar assessment scale as well as subjective and objective assessment of scar erythema

  From enrollment to 3 months after last treatment sessions, where four sessions were given at four-week intervals.

Study Arms (2)

Group A

ACTIVE COMPARATOR

Device: Long pulsed ND: YAG laser

Group B

ACTIVE COMPARATOR

Device: Intense Pulsed Light

Interventions

Long pulsed ND: YAG laser DEVICE

Long Pulsed ND:YAG laser (1064 nm)

Group A

Intense Pulsed Light DEVICE

Intense Pulsed Light (light based modality)

Group B

Eligibility Criteria

• Age: 12 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• Patients of either gender, aged more than 12 years, presenting with an erythematous scar on the head and neck area, traumatic or post-surgical, and of a duration equal to or less than six months.

You may not qualify if:

• \. Patients with post burn scars, scars of more than six months duration, keloids, post acne atrophic erythematous scars or scars that are not located on the head and neck area.
• \. Patients with active bacterial, viral, or fungal cutaneous infection within the scar tissue.
• \. Patients who are pregnant or lactating. 4. Known contraindication to laser therapy. 5. Use of Isotretinoin within the previous 6 months.

Sponsors & Collaborators

• Alexandria University: lead

Study Sites (1)

Alexandria main university hospital, Department of dermatology and venerology.

Alexandria, Alexandria Governorate, 55555, Egypt

Location

MeSH Terms

Conditions

Cicatrix

Interventions

Intense Pulsed Light Therapy

Condition Hierarchy (Ancestors)

Fibrosis; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Phototherapy; Therapeutics

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: May 15, 2026
• First Posted: May 20, 2026
• Study Start: November 16, 2022
• Primary Completion: December 25, 2024
• Study Completion: April 12, 2025
• Last Updated: May 20, 2026

Record last verified: 2026-04

Data Sharing

• IPD Sharing: Will share

Locations

EG (1)