Moxibustion for Nocturia
Evaluation of the Efficacy and Safety of Acupoint Moxibustion for Nocturia: A Pilot Study
1 other identifier
interventional
100
1 country
1
Brief Summary
Nocturia, the interruption of sleep due to nighttime voiding, severely compromises quality of life, emotional health, and overall well-being when occurring twice or more per night. Given that some patients experience inadequate responses to conventional Western therapies or harbor concerns about the long-term side effects of pharmaceuticals, many are turning to Traditional Chinese Medicine (TCM) for alternative solutions. This study utilized a randomized clinical trial design to investigate the efficacy and safety of acupoint moxibustion for nocturia.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for not_applicable
Started Jan 2025
Typical duration for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 1, 2025
CompletedFirst Submitted
Initial submission to the registry
March 4, 2026
CompletedFirst Posted
Study publicly available on registry
May 20, 2026
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 31, 2026
ExpectedStudy Completion
Last participant's last visit for all outcomes
December 31, 2026
May 20, 2026
March 1, 2026
2 years
March 4, 2026
May 17, 2026
Conditions
Outcome Measures
Primary Outcomes (2)
frequency of nocturia
Baseline and Week 3 and Week 6
nocturnal urine volume
Baseline and Week 3 and Week 6
Secondary Outcomes (7)
International Prostate Symptom Score (IPSS)
Baseline and Week 3 and Week 6
Overactive Bladder Symptom Score (OABSS)
Baseline and Week 3 and Week 6
Quality of Life (QoL)
Baseline and Week 3 and Week 6
Pittsburgh Sleep Quality Index (PSQI)
Baseline and Week 3 and Week 6
Abdominal muscle tension
Baseline and Week 3 and Week 6
- +2 more secondary outcomes
Study Arms (2)
Moxibustion
EXPERIMENTALControl
NO INTERVENTIONInterventions
Eligibility Criteria
You may qualify if:
- Patients aged 40 years or older.
- Experiencing two or more nocturia episodes per night.
You may not qualify if:
- Active urinary tract infection (UTI).
- Poorly controlled diabetes mellitus (defined as HbA1c \> 6.5%).
- Presence of a neurogenic bladder caused by conditions such as multiple sclerosis, Parkinson's disease, stroke, spinal cord injury, or nerve damage resulting from major pelvic surgery.
- Severe congestive heart failure (New York Heart Association \[NYHA\] functional class \> II).
- Use of other Traditional Chinese Medicine (TCM) therapies for nocturia symptoms within the past month (30 days).
- Pregnant women.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation
Hualien City, Taiwan
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- OUTCOMES ASSESSOR
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
March 4, 2026
First Posted
May 20, 2026
Study Start
January 1, 2025
Primary Completion (Estimated)
December 31, 2026
Study Completion (Estimated)
December 31, 2026
Last Updated
May 20, 2026
Record last verified: 2026-03