Change of Knee Phenotype After Total Hip Arthroplasty

NCT07597538 | Recruiting

• 1 other identifier: THA-Knee-phenotype-2026
• Study Type: observational
• Target: 500
• Locations: 1 country
• Sites: 1

Brief Summary

this study evaluates changes in knee phenotype after total hip arthroplasty using radiographic assessment of coronal alignment in a prospective cohort of patients

Conditions

Coronal Plane Alignment of the Knee; Knee Phenotype Changes After THA

Keywords

knee phenotype; full length radiograph; CPAk

Outcome Measures

Primary Outcomes (1)

• knee phenotype change following total hip arthroplasty

  knee phenotype change will be assessed using full-length radiographs by comparing coronal alignment parameters before and after total hip arthroplasty

  Immediately postoperatively"

Eligibility Criteria

• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

the study population will include any patient undergoing primary unilateral total hip arthroplasty for hip joint pathology .patient will be recruited consecutively from the orthopedic surgery department . all eligible patients will be assessed preoperatively and followed postoperatively with full length lower limb radiographs to evaluate changes in knee phenotype and coronal alignment

You may qualify if:

• patients scheduled for primary unilateral total hip arthroplasty
• patient with hip joint pathology indicated for THA ( osteoarthritis )
• ability to provide informed consent
• availability for pre and post- operative radiographic follow-up

You may not qualify if:

• refusal to participate or withdraw consent
• incomplete radiographic data or loss to follow up
• previous surgery on the ipsilateral hip or knee
• patients with neuromuscular disorders affecting alignment

Sponsors & Collaborators

• Nader Ahmed Sayed Abdelhamed: lead

Study Sites (1)

Department of orthopedic surgery faculty of medicine assiut university

Asyut, Asyut Governorate, 71515, Egypt

RECRUITING

Study Officials

• mohamed kamal abdelnasser, MD professor orthopedic

  faculty of medicine assiut univerisity

  PRINCIPAL INVESTIGATOR

• mohamed anter ali, MD Doctor orthopedic surgery

  Assiut University

  PRINCIPAL INVESTIGATOR

Central Study Contacts

nader ahmed sayed, MD (resident)

CONTACT

+201029975354; Nader.17289651@med.aun.edu.eg

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: resident orthopedic surgery

Study Record Dates

• First Submitted: April 10, 2026
• First Posted: May 19, 2026
• Study Start: February 1, 2026
• Primary Completion (Estimated): February 1, 2028
• Study Completion (Estimated): August 1, 2028
• Last Updated: May 19, 2026

Record last verified: 2026-05

Locations

EG (1)