Foundations for Prescribing Song-Based Therapies: A Quantitative Comparison of Laryngeal Exercises

NCT07595315 | Withdrawn

• 2 other identifiers: SINGS TL1TL1TR002368
• Study Type: interventional
• Target: N/A
• Locations: 0 countries
• Sites: N/A

Brief Summary

SINGS explores the therapeutic potential of song-based exercises for treating dysphagia in geriatric populations. The project aims to compare the effectiveness of song-based tasks with traditional speech-language pathology (SLP) exercises using advanced tools such as surface electromyography (sEMG) and functional neuroimaging. In addition to quantifying functional activity during therapy, the study will assess patient compliance, satisfaction, and long-term swallowing outcomes, with a focus on improving quality of life through innovative, enjoyable therapies.

Conditions

Dysphagia

Keywords

Song-based therapy; Music therapy; Surface EMG; EEG

Outcome Measures

Primary Outcomes (2)

• Muscle Activation

  Surface EMG readings between SBT and SLP tasks.

  Day 1 (single 90-minute study visit)

• EEG

  Similar regional neural activity measured by EEG between SBT and SLP tasks.

  Day 1 (single 90-minute study visit)

Secondary Outcomes (3)

• EAT-10 Total Score

  Day 1 (single study visit)

• Self-reported tobacco and e-cigarette use

  Day 1 (single study visit); assesses past 30 days and lifetime history as applicable

• Patient Satisfaction Survey

  Day 1 (single study visit)

Study Arms (2)

Healthy cohort without prescribed dysphagia

PLACEBO COMPARATOR

This cohort of healthy individuals will help establish mechanisms of therapy protocols to apply in future studies on target population.

Other: Dysphagia Treatment Protocol

SINGS Intervention

EXPERIMENTAL

The SINGS arm will be completed by all members in the cohort.

Other: Dysphagia Treatment Protocol

Interventions

Dysphagia Treatment Protocol OTHER

The SINGS arm will be completed by all members in the cohort.

Also known as: SINGS

Healthy cohort without prescribed dysphagia; SINGS Intervention

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Healthy Adults

You may not qualify if:

• History of head and neck cancer, radiation to the neck, and/or other head and neck based surgeries\*
• Formal Dysphagia diagnosis\*
• Formal GERD diagnosis\*
• Adults unable to consent
• Individuals who are not yet adults (infants, children, teenagers)
• Prisoners

Sponsors & Collaborators

• University of Kansas Medical Center: lead
• National Center for Advancing Translational Sciences (NCATS): collaborator

MeSH Terms

Conditions

Deglutition Disorders

Condition Hierarchy (Ancestors)

Esophageal Diseases; Gastrointestinal Diseases; Digestive System Diseases; Pharyngeal Diseases; Otorhinolaryngologic Diseases

Study Officials

• Jennifer Villwock, MD

  University of Kansas Medical Center

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: Participants are prospectively assigned to perform predefined speech-language pathology exercises and song-based tasks during a single study visit while EEG and surface EMG are recorded for mechanistic comparison. This is a basic science / physiologic study conducted in healthy adults with a cross-sectional, single-visit (\~90 minutes) design.

Study Record Dates

• First Submitted: November 20, 2024
• First Posted: May 19, 2026
• Study Start: June 1, 2025
• Primary Completion: October 15, 2025
• Study Completion: December 15, 2025
• Last Updated: May 19, 2026

Record last verified: 2026-05