NCT07593768

Brief Summary

As part of a prospective study, to evaluate the effect of periodontitis on the course of hypertension at baseline, during 6 and 12 months

Trial Health

55
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
200

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Oct 2023

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
active not recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 10, 2023

Completed
1.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2025

Completed
8 months until next milestone

First Submitted

Initial submission to the registry

May 12, 2026

Completed
6 days until next milestone

First Posted

Study publicly available on registry

May 18, 2026

Completed
12 days until next milestone

Study Completion

Last participant's last visit for all outcomes

May 30, 2026

Completed
Last Updated

May 18, 2026

Status Verified

May 1, 2026

Enrollment Period

1.9 years

First QC Date

May 12, 2026

Last Update Submit

May 12, 2026

Conditions

PeriodontitisArterial Hypertension

Keywords

cardiovascular riskarterial hypertensioninflammationperiodontitis

Outcome Measures

Primary Outcomes (2)

  • Triglyceride level

    Triglyceride level

    12 months from inclusion

  • Low density lipoprotein level

    Low density lipoprotein level

    12 months from inclusion

Study Arms (2)

Periodontitis group

Diagnostic Test: Orthopantomography

Control group

Diagnostic Test: Orthopantomography

Interventions

OrthopantomographyDIAGNOSTIC_TEST

Orthopantomography

Control groupPeriodontitis group

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

The study is set to include 200 patients (both sexes) over 18 years of age with arterial hypertension who signed the informed consent form for participation in the study: 100 patients with periodontitis and 100 patients without periodontitis - control group

You may qualify if:

  • Age (18 years and older)
  • Written informed consent signed

You may not qualify if:

  • Failure to follow up

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University hospital #1

Moscow, Russia

Location

MeSH Terms

Conditions

HypertensionPeriodontitisInflammation

Interventions

Radiography, Panoramic

Condition Hierarchy (Ancestors)

Vascular DiseasesCardiovascular DiseasesPeriodontal DiseasesMouth DiseasesStomatognathic DiseasesPathologic ProcessesPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Radiography, DentalRadiographyDiagnostic ImagingDiagnostic Techniques and ProceduresDiagnosisDiagnosis, OralDentistry

Study Officials

  • Olga Trushina, MD, PhD

    Sechenov University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 12, 2026

First Posted

May 18, 2026

Study Start

October 10, 2023

Primary Completion

September 1, 2025

Study Completion

May 30, 2026

Last Updated

May 18, 2026

Record last verified: 2026-05

Data Sharing

IPD Sharing
Will not share

Locations

RU(1)