NCT07592559

Brief Summary

This study employs transcranial direct current stimulation (tDCS) to investigate the role of the orbitofrontal cortex (OFC) in processing gaze and arrow cues.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
60

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jun 2022

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 2, 2022

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 30, 2022

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

December 8, 2022

Completed
3.4 years until next milestone

First Submitted

Initial submission to the registry

April 23, 2026

Completed
25 days until next milestone

First Posted

Study publicly available on registry

May 18, 2026

Completed
Last Updated

May 18, 2026

Status Verified

May 1, 2026

Enrollment Period

5 months

First QC Date

April 23, 2026

Last Update Submit

May 11, 2026

Conditions

tDCSCues TypeSOACongruency

Keywords

transcranial direct current stimulationgaze cueing effectorbitofrontal cortex

Outcome Measures

Primary Outcomes (1)

  • Reaction time to the judgment of the target location.

    The primary analysis focused on the reaction times for judging the target location under each condition.

    1 hour

Secondary Outcomes (1)

  • Magnitude of the cueing effect

    1 hour

Study Arms (3)

anodal tDCS

EXPERIMENTAL

anodal tDCS rOFC

Behavioral: Gaze cuesBehavioral: Arrow cuesBehavioral: SOA 200 msBehavioral: SOA 600 msBehavioral: CongruentBehavioral: Incongruent

cathodal tDCS

EXPERIMENTAL

cathodal tDCS rOFC

Behavioral: Gaze cuesBehavioral: Arrow cuesBehavioral: SOA 200 msBehavioral: SOA 600 msBehavioral: CongruentBehavioral: Incongruent

sham tDCS

SHAM COMPARATOR

sham tDCS rOFC

Behavioral: Gaze cuesBehavioral: Arrow cuesBehavioral: SOA 200 msBehavioral: SOA 600 msBehavioral: CongruentBehavioral: Incongruent

Interventions

Gaze cuesBEHAVIORAL

use eye gaze images as cues

anodal tDCScathodal tDCSsham tDCS
Arrow cuesBEHAVIORAL

use arrow images as cues

anodal tDCScathodal tDCSsham tDCS
SOA 200 msBEHAVIORAL

The stimulus onset asynchrony (SOA) between the cue and the target was 200 ms.

anodal tDCScathodal tDCSsham tDCS
SOA 600 msBEHAVIORAL

The stimulus onset asynchrony (SOA) between the cue and the target was 600 ms.

anodal tDCScathodal tDCSsham tDCS
CongruentBEHAVIORAL

The cue is spatially congruent with the target.

anodal tDCScathodal tDCSsham tDCS
IncongruentBEHAVIORAL

The cue is spatially incongruent with the target.

anodal tDCScathodal tDCSsham tDCS

Eligibility Criteria

Age18 Years - 30 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • healthy subjects without past or current psychiatric or neurological disorders

You may not qualify if:

  • history of head injury
  • no implants in the head
  • medical or psychiatric illness.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

School of Foreign Languages, University of Electronic Science and Technology of China

Chengdu, Sichuan, 611731, China

Location

MeSH Terms

Interventions

Culturally Competent Care

Intervention Hierarchy (Ancestors)

Delivery of Health CarePatient Care ManagementHealth Services AdministrationHealth Care Quality, Access, and Evaluation

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
BASIC SCIENCE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

April 23, 2026

First Posted

May 18, 2026

Study Start

June 2, 2022

Primary Completion

October 30, 2022

Study Completion

December 8, 2022

Last Updated

May 18, 2026

Record last verified: 2026-05

Locations

CN(1)