Horizontal Ridge Augmentation in Maxillary Esthetic Zone Using Bovine Bone Graft Versus Extended Sticky Bone With Simultaneous Implant Placement

NCT07589426 | Completed DMC

• 1 other identifier: Ms.25.04.21
• Study Type: interventional
• Target: 16
• Locations: 1 country
• Sites: 2

Brief Summary

This research is designed to evaluate and compare the clinical and radiographic outcomes of bovine bone graft (Medpark) versus extended sticky bone used for horizontal augmentation of atrophied esthetic area of maxillary ridge associated with simultaneous implant placement.

Conditions

Horizontal Alveolar Ridge Resorption

Keywords

: Medpark; Extended sticky bone; Horizontal ridge augmentation; soft tissue healing; implant stability; bone volume.

Outcome Measures

Primary Outcomes (1)

• Implant Stability Quotient (ISQ) Values Assessed by Resonance Frequency Analysis

  Implant stability was assessed using resonance frequency analysis (RFA) with the Osstell device and expressed as Implant Stability Quotient (ISQ) values. ISQ scores range from 1 to 100, with higher scores indicating greater implant stability and osseointegration. High stability: ISQ \> 70 Medium stability: ISQ 60-69 Low stability: ISQ \< 60 Measurements were recorded immediately after implant placement and at the 6-month follow-up.

  Baseline and 6 months after implant placement

Study Arms (2)

Eight dental implants were inserted simultaneously with horizontal ridge augmentation using Medpark

EXPERIMENTAL

For group I, Medpark bone graft was prepared by hydration with sterile saline, gentle mixing, and allowed to partially set before application to the defect site. For group II, extended sticky bone (ESB) was prepared by centrifugation of autologous blood followed by preparation of ALB-PRF and mixing with bone particulates (50:50 allograft: xenograft) to obtain the final graft materia

Procedure: oral surgery

Eight dental implants were inserted simultaneously with horizontal ridge augmentation using extended

EXPERIMENTAL

Procedure: oral surgery

Interventions

oral surgery PROCEDURE

The oral cavity was prepared using 0.12% chlorhexidine mouth rinse for one minute. Local anesthesia was administered using articaine 4% with 1:100,000 epinephrine. A full-thickness mucoperiosteal flap was reflected using a crestal horizontal incision with vertical releasing incisions to expose the surgical site. Osteotomy preparation was performed using a pilot drill to the planned depth at 800-850 rpm under copious sterile saline irrigation, followed by sequential drilling according to the manufacturer's protocol until the final implant size was achieved. The sterile implant was then inserted using a ratchet wrench. Implant stability was immediately assessed using resonance frequency analysis (Osstell device), and cover screws were subsequently placed. For group I, Medpark bone graft was prepared by hydration with sterile saline, gentle mixing, and allowed to partially set before application to the defect site. For group II, extended sticky bone (ESB) was prepared b

Eight dental implants were inserted simultaneously with horizontal ridge augmentation using Medpark; Eight dental implants were inserted simultaneously with horizontal ridge augmentation using extended

Eligibility Criteria

• Age: 18 Years - 45 Years
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Patient aged 18-45 years, Cooperative patient with high motivation and acceptable oral hygiene, maxillary narrow ridge in the esthetic zone that needed horizontal bone augmentation. (Class I Siebert classification) (24),No deep undercut at the ridge in the buccal aspect, The presence of enough keratinized gingiva(≥3mm).(25), sufficient inter-arch space to accommodate the future prosthesis. (26) , and Patients able to comply with the required recall visits.

You may not qualify if:

• Local and / or systemic conditions that contraindicate the placement of dental implant or surgery, smokers, pregnancy and parafunctional habits, including bruxism and clenching.

Sponsors & Collaborators

• Mansoura University: lead

Study Sites (2)

Amira Attia

Al Mansurah, Egypt

Location

Mansoura University

Al Mansurah, Egypt

Location

MeSH Terms

Interventions

Surgery, Oral

Intervention Hierarchy (Ancestors)

Dentistry

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: May 3, 2026
• First Posted: May 15, 2026
• Study Start: November 1, 2025
• Primary Completion: April 1, 2026
• Study Completion: May 1, 2026
• Last Updated: May 15, 2026

Record last verified: 2026-05

Data Sharing

• IPD Sharing: Will not share

Locations

EG (2)