NCT07587398

Brief Summary

To test the effect of acupuncture in treating headaches, as well as co-measures of stress and emotional distress, in participants during the hormonal stimulation phase prior to an oocyte retrieval. Subjects were identified females at birth experiencing a headache while undergoing a hormone stimulation cycle as part of in vitro fertilization or oocyte cryopreservation. Intervention was an individualized acupuncture treatment with needle retention for thirty minutes. Main outcome measured were headache intensity, level of stress, level of emotional distress.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
37

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Feb 2023

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 27, 2023

Completed
1.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 22, 2024

Completed
10 days until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2024

Completed
1.7 years until next milestone

First Submitted

Initial submission to the registry

April 30, 2026

Completed
14 days until next milestone

First Posted

Study publicly available on registry

May 14, 2026

Completed
Last Updated

May 14, 2026

Status Verified

May 1, 2026

Enrollment Period

1.4 years

First QC Date

April 30, 2026

Last Update Submit

May 7, 2026

Conditions

HeadacheStress (Psychology)Emotional Distress

Keywords

AcupunctureHeadacheIVFStressEgg Stimulation

Outcome Measures

Primary Outcomes (1)

  • Headache Intensity

    Level of headache intensity scored on a scale of 0-10

    Change from before intervention to after intervention for any number of acupuncture treatments over the length of a stimulation cycle (about 2 weeks)

Secondary Outcomes (2)

  • Stress

    Change from before intervention to after intervention for any number of acupuncture treatments over the length of a stimulation cycle (about 2 weeks)

  • Emotional Distress

    Change from before intervention to after intervention for any number of acupuncture treatments over the length of a stimulation cycle (about 2 weeks)

Study Arms (1)

Acupuncture

EXPERIMENTAL

Acupuncture treatment with 30 minute needle retention

Procedure: Acupuncture

Interventions

AcupuncturePROCEDURE

Acupuncture treatment with 30 minute needle retention

Acupuncture

Eligibility Criteria

Age29 Years - 49 Years
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • adult biological female
  • participating in an active hormone stimulation cycle
  • receiving acupuncture treatment for fertility support at SCRC in Beverly Hills with the second investigator
  • experiencing a headache

You may not qualify if:

  • participants undergoing a medicated IUI

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Southern California Reproductive Center

Beverly Hills, California, 90210, United States

Location

MeSH Terms

Conditions

Headache

Interventions

Acupuncture Therapy

Condition Hierarchy (Ancestors)

PainNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Complementary TherapiesTherapeutics

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 30, 2026

First Posted

May 14, 2026

Study Start

February 27, 2023

Primary Completion

July 22, 2024

Study Completion

August 1, 2024

Last Updated

May 14, 2026

Record last verified: 2026-05

Locations

US(1)