Effects of Cervical and Oculomotor Exercises on Functional Status, Balance, and Proprioception in Chronic Ankle Instability

NCT07581535 | Not Yet Recruiting

• 1 other identifier: 2586
• Study Type: interventional
• Target: 38
• Locations: 1 country
• Sites: 1

Brief Summary

Effects of Cervical and Oculomotor Exercises on Functional Status, Balance, and Proprioception in Chronic Ankle Instability

Conditions

Chronic Ankle Instability, CAI

Keywords

Postural Balance; Proprioception; Rehabilitation; Ankle Instability

Outcome Measures

Primary Outcomes (2)

• Y-Balance Test

  Dynamic balance performance assessed using balance tests (Y-Balance Test)

  Baseline and post-intervention (after 4 weeks)

• Foot and Ankle Ability Measure (FAAM)

  Functional status assessed using the Foot and Ankle Ability Measure (FAAM) The daily living activities subscale contains 21 items; the minimum score is 0 and the maximum score is 84. The sports subscale consists of 8 items; the minimum score is 0 and the maximum score is 32. A higher score represents a higher level of physical function.

  Baseline and post-intervention (after 4 weeks)

Secondary Outcomes (6)

• Ankle Joint Position Error Test

  Baseline and post-intervention (after 4 weeks)

• Weight Bearing Lunge Test

  Baseline and post-intervention (after 4 weeks)

• Computerized balance assessment

  Baseline and post-intervention (after 4 weeks)

• Side Hop Test

  Baseline and post-intervention (after 4 weeks)

• Ankle Pain

  Baseline and post-intervention (after 4 weeks)

Study Arms (2)

Conventional Treatment + Cervical and Oculomotor Exercises

EXPERIMENTAL

Participants in the experimental group will receive a conventional rehabilitation program including mobility, strengthening, balance, and proprioceptive exercises targeting the ankle joint. In addition, they will perform cervical stabilization and oculomotor exercises. The intervention will be conducted for 4 weeks, with 3 sessions per week. Participants will follow a home exercise program that includes ankle mobility, strengthening, balance, and oculomotor exercises on days when they do not attend the clinic.

Other: Exercise

Conventional Treatment

ACTIVE COMPARATOR

Participants in the control group will receive a conventional rehabilitation program consisting of mobility, strengthening, balance, and proprioceptive exercises targeting the ankle joint. The intervention will be conducted for 4 weeks, with 3 sessions per week. Participants will follow a home exercise program that includes ankle mobility, strengthening and balance exercises on days when they do not attend the clinic.

Other: Exercise

Interventions

Exercise OTHER

Participants in the experimental group will receive a conventional rehabilitation program including mobility, strengthening, balance, and proprioceptive exercises targeting the ankle joint. In addition, they will perform cervical stabilization and oculomotor exercises.

Conventional Treatment + Cervical and Oculomotor Exercises

Eligibility Criteria

• Age: 18 Years - 45 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Diagnosed with unilateral chronic ankle instability (CAI) in accordance with the International Ankle Consortium recommendations
• A history of at least one significant lateral ankle sprain that occurred at least 12 months prior to participation, resulting in inflammatory symptoms such as pain and swelling and causing at least one day of interruption in physical activity
• A history of "giving way" and/or recurrent ankle sprains and/or a feeling of instability in the affected ankle within the past 6 months
• A Cumberland Ankle Instability Tool (CAIT) score of ≤ 25

You may not qualify if:

• History of surgery or fracture in the lower extremities or spine
• Acute musculoskeletal injury affecting other joints of the lower extremity within the past 3 months (e.g., sprains, fractures) that impaired joint integrity and function and caused at least one day of interruption in physical activity
• History of injection in the affected ankle
• History of ankle sprain in the affected extremity within the past 4 weeks
• Presence of systemic musculoskeletal disorders, neurological disorders, vestibular disorders, or any other condition that may affect balance or sensory function
• Previous participation in any rehabilitation program for the ankle or cervical region
• History of head or neck trauma or diagnosed pathology within the past 12 months
• History of neck pain greater than 3/10 in severity within the past 12 months

Sponsors & Collaborators

• Izmir Katip Celebi University: lead
• Izmir Bakircay University: collaborator

Study Sites (1)

Izmir Katip Celebi University Physiotherapy and Rehabilitation Department

Izmir, Çiğli, 35650, Turkey (Türkiye)

Location

MeSH Terms

Interventions

Exercise

Intervention Hierarchy (Ancestors)

Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Officials

• Damla KARABAY, Assistant Professor

  Izmir Katip Çelebi University

  STUDY CHAIR

• Simge N UNGAN, Physiotherapist (Bachelor)

  Izmir Katip Çelebi University

  PRINCIPAL INVESTIGATOR

• Sercan Çapkın, Associate Professor

  Izmir Bakırçay University

  STUDY DIRECTOR

Central Study Contacts

Simge N UNGAN, Phsiotherapist

CONTACT

+90 507 648 5776; ungansimgenur@gmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Phsiotherapist

Study Record Dates

• First Submitted: April 29, 2026
• First Posted: May 12, 2026
• Study Start: May 7, 2026
• Primary Completion (Estimated): June 7, 2027
• Study Completion (Estimated): June 7, 2027
• Last Updated: May 12, 2026

Record last verified: 2026-05

Locations

TU (1)