Correlation Between Nasal Septal Deviation and Transverse Maxillary Deficiency on CT Scans

NCT07579091 | Completed

• 1 other identifier: 2025PI134
• Study Type: observational
• Target: 223
• Locations: 1 country
• Sites: 1

Brief Summary

The maxillary bones and the nasal septum are interconnected structures. The nasal septum acts as a growth center that facilitates normal maxillofacial growth and development. The objective of this study is to evaluate the presence or absence of septal deviation, as well as its degree of severity, within two adult population groups with or without maxillary transverse deficiency. This is a retrospective CT scan study. While several studies have been conducted in this field, our study is original in its approach to: maxillary transverse deficiency as a measure of the transverse dimension of the maxilla, the use of CT scans as the radiological medium for evaluating the primary endpoint, and finally, the specific method used to measure septal deviation. If a correlation exists between the two, it would be interesting to investigate whether maxillary transverse deficiency leads to septal deviation, or if septal deviation contributes to maxillary deficiency through nasal obstruction. This could highlight the importance of early management of both maxillary transverse deficiency and nasal obstruction. In adult patients, it could support the idea of performing a single combined procedure involving maxillary expansion and septoplasty, which would reduce comorbidities and risks; ultimately representing a true benefit for the patient.

Conditions

Maxillary Transversal Deficiency

Keywords

transverse maxillary deficiency; endognathia; septal deviation; CT scan; nasal septal deviation

Outcome Measures

Primary Outcomes (1)

• Nasal septal deviation measured by coronal CT scan

  one day

Secondary Outcomes (6)

• Width of the piriform apertures measured by coronal CT scan

  one day

• Depth of the palatal vault measured by sagittal CT scan

  one day

• location of the septal deviation measured by coronal CT scan

  one day

• degree of septal deviation and depth of the palatal vault

  one day

• width of the piriform apertures and depth of the palatal vault

  one day

Study Arms (2)

Patient with maxillary transverse deficiency

Patient with maxillary constriction

Patient without maxillary transverse deficiency

Patient without maxillary constriction

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Deceased from natural causes and underwent a whole-body CT scan between 2010 and 2017, in the State of New Mexico (USA)

You may qualify if:

• Adult with completed growth (\> 18 years old)
• Deceased from natural causes and underwent a whole-body CT scan between 2010 and 2017, in the State of New Mexico (USA)
• Presence of maxillar and mandibular teeth from first molar to first molar (from 6 to 6)
• No body decomposition at the time of the CT scan

You may not qualify if:

• History of maxillofacial surgery or trauma
• Congenital craniofacial pathologies or anomalies
• Presence of maxillary or mandibular orthodontic appliances (or retainers)

Sponsors & Collaborators

• Central Hospital, Nancy, France: lead

Study Sites (1)

Delcampe

Nancy, 54000, France

Location

Study Officials

• Bart Vande Vannet

  Central Hospital, Nancy, France

  STUDY DIRECTOR

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: PuPh

Study Record Dates

• First Submitted: April 29, 2026
• First Posted: May 11, 2026
• Study Start: February 7, 2026
• Primary Completion: March 10, 2026
• Study Completion: April 7, 2026
• Last Updated: May 11, 2026

Record last verified: 2026-04

Locations

FR (1)