The Effect of Self-Acupressure on Blood Pressure, Stress, and Well-Being Levels in Individuals With Hypertension

NCT07577973 | Not Yet Recruiting

• 1 other identifier: AIBU-HTN-ACUP-2026-01
• Study Type: interventional
• Target: 72
• Locations: 1 country
• Sites: 1

Brief Summary

This randomized controlled trial examines the effects of nurse-led self-acupressure at HT7, LI4, PC6, and EX3 points on blood pressure, stress, and well-being in adults with primary hypertension. Participants are randomized to real acupressure, sham acupressure, or usual care groups for 2 weeks.

Conditions

PRIMARY HYPERTENSION

Keywords

Acupressure Hypertension Self-care Nursing Stress Well-being Randomized Controlled Trial

Outcome Measures

Primary Outcomes (1)

• change in blood pressure

  change from baseline in systolic and diastolic blood pressure measured using an automated office blood pressure monitor at 2 weeks

  baseline and week 2

Secondary Outcomes (2)

• change in perceived stress

  baseline, week 2

• change in mental well-being

  baseline, week 2

Study Arms (3)

Real Acupressure Group

EXPERIMENTAL

participants receive acupressure on bilateral HT7,LI4,PC6 EX3 points. pressure applied for 15 seconds per point, 3 days per week, for 2 weeks

Behavioral: Real Acupressure

sham/placebo

SHAM COMPARATOR

Participants receive sham acupressure on non-acupoints located 1-1.5 cm away from HT7, LI4 , PC6, and EX3 points. Pressure applied for 15 seconds per site, 3 days per week, for 2 weeks to maintain participant blinding

Behavioral: sham acupressure

control

ACTIVE COMPARATOR

Participants receive usual care for hypertension including prescribed antihypertensive medications and routine clinical nursing follow-up for 2 weeks. No acupressure intervention applied.

Other: Usual Care

Interventions

Real Acupressure BEHAVIORAL

Acupressure applied to HT7 (Shenmen), LI4 (Hegu), PC6 (Neiguan) bilaterally, and EX3 (Yintang). Pressure applied for 15 seconds per point, 3 days per week for 2 weeks by trained researcher. Total session duration approximately 1 minute.

Real Acupressure Group

sham acupressure BEHAVIORAL

light pressure applied to non-acupoint sites 1-1.5 cm from HT7İLI4,PC6 and EX3 points for 15 seconds per site,3 days per week for 2 weeks

sham/placebo

Usual Care OTHER

Standard hypertension management including prescribed antihypertensive medication and routine clinical nursing follow-up for 2 weeks. No acupressure applied.

control

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Aged 18-65 years
• Diagnosed with primary hypertension (Stage 1 or 2)
• Systolic blood pressure 130-179 mmHg or diastolic 80-109 mmHg
• Taking antihypertensive medication
• Able to understand and communicate in Turkish
• Willing to provide written informed consent

You may not qualify if:

• Secondary hypertension
• Pregnancy or lactation
• Severe cardiovascular disease (heart failure, myocardial infarction within 6 months)
• Stroke history within 6 months
• Skin lesions or infection at acupressure sites (HT7, LI4, PC6, EX3)
• Peripheral neuropathy affecting sensation
• Current use of anticoagulant therapy
• Participation in another clinical trial within 30 days

Sponsors & Collaborators

• Abant Izzet Baysal University: lead

Study Sites (1)

A Family Health Center in Duzce

Düzce, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Essential Hypertension

Condition Hierarchy (Ancestors)

Hypertension; Vascular Diseases; Cardiovascular Diseases

Study Officials

• Saadet Can Cicek, Associate Professor,PhD

  Abant Izzet Baysal University

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Seymanur Ozdemir Arslan, MSc,Phd Candidate

CONTACT

+90 0380 523 7827; seymanurarslan@duzce.edu.tr

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: SUPPORTIVE CARE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Asst. Prof.Saadet Can Cicek,Phd

Model Details: Participants will be randomized into 3 groups:real acupressure, sham acupressure, and usual care

Study Record Dates

• First Submitted: May 5, 2026
• First Posted: May 11, 2026
• Study Start (Estimated): June 1, 2026
• Primary Completion (Estimated): September 1, 2026
• Study Completion (Estimated): October 1, 2026
• Last Updated: May 14, 2026

Record last verified: 2026-05

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)